Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FS841_RS17545 Genome accession   NZ_CP043937
Coordinates   3643246..3643878 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain RM14516     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3638246..3648878
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FS841_RS17520 (FS841_17660) yheS 3638415..3640328 (+) 1914 WP_000634840.1 ABC transporter ATP-binding protein -
  FS841_RS17525 (FS841_17665) yheT 3640328..3641350 (+) 1023 WP_000057395.1 hydrolase -
  FS841_RS17530 (FS841_17670) yheU 3641344..3641562 (+) 219 WP_000907085.1 YheU family protein -
  FS841_RS17535 (FS841_17675) prkB 3641616..3642485 (+) 870 WP_001274680.1 phosphoribulokinase -
  FS841_RS17540 (FS841_17680) yhfA 3642540..3642944 (-) 405 WP_001148908.1 OsmC family protein -
  FS841_RS17545 (FS841_17685) crp 3643246..3643878 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  FS841_RS17550 (FS841_17690) yhfK 3643929..3646019 (+) 2091 WP_001309799.1 YccS/YhfK family putative transporter -
  FS841_RS17555 (FS841_17695) argD 3646086..3647306 (-) 1221 WP_000190012.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  FS841_RS17560 (FS841_17700) pabA 3647392..3647955 (-) 564 WP_000601862.1 aminodeoxychorismate synthase component 2 -
  FS841_RS17565 (FS841_17705) fic 3647987..3648589 (-) 603 WP_001280634.1 putative adenosine monophosphate-protein transferase Fic -
  FS841_RS17570 (FS841_17710) yhfG 3648579..3648746 (-) 168 WP_000736851.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=339406 FS841_RS17545 WP_000242755.1 3643246..3643878(+) (crp) [Escherichia coli strain RM14516]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=339406 FS841_RS17545 WP_000242755.1 3643246..3643878(+) (crp) [Escherichia coli strain RM14516]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAGGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACTGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467