Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   ERO09_RS02325 Genome accession   NZ_CP035368
Coordinates   490684..491352 (+) Length   222 a.a.
NCBI ID   WP_049357048.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain LC_1315_18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 485684..496352
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ERO09_RS02290 (ERO09_02280) rpmG 486534..486704 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  ERO09_RS02295 (ERO09_02285) rpmB 486716..486952 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  ERO09_RS02300 (ERO09_02290) radC 487170..487835 (-) 666 WP_128787004.1 DNA repair protein RadC -
  ERO09_RS02305 (ERO09_02295) coaBC 488039..489241 (+) 1203 WP_128787005.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  ERO09_RS02310 (ERO09_02300) dut 489315..489770 (+) 456 WP_049357052.1 dUTP diphosphatase -
  ERO09_RS02315 (ERO09_02305) slmA 489774..490427 (+) 654 WP_049357050.1 nucleoid occlusion factor SlmA -
  ERO09_RS02320 (ERO09_02310) - 490449..490667 (+) 219 WP_005695554.1 YheU family protein -
  ERO09_RS02325 (ERO09_02315) crp 490684..491352 (+) 669 WP_049357048.1 cAMP-activated global transcriptional regulator CRP Regulator
  ERO09_RS02330 (ERO09_02320) nagE 491862..493328 (-) 1467 WP_128787006.1 N-acetylglucosamine-specific PTS transporter subunit IIBC -
  ERO09_RS02335 (ERO09_02325) - 493546..494235 (+) 690 WP_005698367.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  ERO09_RS02340 (ERO09_02330) - 494247..495185 (+) 939 WP_005695558.1 N-acetylmannosamine kinase -
  ERO09_RS02345 (ERO09_02335) - 495178..496044 (+) 867 WP_128787007.1 MurR/RpiR family transcriptional regulator -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 25161.93 Da        Isoelectric Point: 6.6938

>NTDB_id=339344 ERO09_RS02325 WP_049357048.1 490684..491352(+) (crp) [Haemophilus parainfluenzae strain LC_1315_18]
MSEDVELLEEQKPQDDEQQRDPALDWFLTHCHLHKYPAKSTLIHAGEDANILYFLIKGTVMVSSKDDEGKEMILSYLGAG
QFFGEAGLFDEGSKRSAWVKTKTPCEIAEISYKKYRQLIQINPEILMFLTSQLSKRLQNTSRQVTNLAFLDVAGRIAQAL
MHLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGTR

Nucleotide


Download         Length: 669 bp        

>NTDB_id=339344 ERO09_RS02325 WP_049357048.1 490684..491352(+) (crp) [Haemophilus parainfluenzae strain LC_1315_18]
ATGTCAGAAGATGTAGAATTACTTGAAGAACAAAAGCCTCAGGATGATGAGCAGCAACGCGATCCTGCGCTTGATTGGTT
CCTAACACATTGCCATTTACATAAATATCCAGCAAAGTCGACTTTAATTCATGCTGGGGAGGATGCCAATATTCTGTATT
TCTTAATTAAAGGAACAGTAATGGTGTCATCAAAAGATGACGAAGGCAAAGAAATGATTTTATCTTATTTGGGGGCTGGG
CAATTTTTTGGTGAAGCAGGTTTATTTGATGAGGGATCGAAACGTTCTGCTTGGGTGAAAACCAAAACGCCTTGTGAAAT
TGCGGAAATTTCCTATAAAAAATATCGTCAGCTTATTCAAATTAATCCTGAGATTTTAATGTTTCTTACTTCTCAGTTAT
CAAAACGCTTGCAAAATACCTCTCGACAAGTGACTAACTTGGCCTTTTTGGATGTGGCAGGGCGTATTGCTCAGGCGCTT
ATGCATCTAGCAAAACAGCCTGAAGCCATGACTCATCCGGATGGTATGCAGATTAAAATCACGCGCCAGGAAATCGGTCA
AATGGTGGGTTGTTCTCGTGAAACCGTAGGGCGAATAATTAAGATGCTGGAAGATCAAAATCTAATTCATGCGCACGGCA
AAACCATTGTGGTTTATGGCACTCGATAG

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(34-120)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(154-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

86.161

100

0.869
  crp Vibrio cholerae strain A1552

73.529

91.892

0.676
  crp Acinetobacter baumannii D1279779

46.231

89.64

0.414

Multiple sequence alignment