Detailed information NTG0339202

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ESP48_RS08350
• Genome accession: NZ_CP035306
• Coordinates: 1546943..1547944 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain IDCC2201
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1541943..1552944

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ESP48_RS08330 (ESP48_08330)	smpB	1543050..1543514 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
ESP48_RS08335 (ESP48_08335)	-	1543668..1545074 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
ESP48_RS08340 (ESP48_08340)	-	1545076..1545441 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
ESP48_RS08345 (ESP48_08345)	-	1545544..1546629 (-)	1086	WP_011680935.1	M24 family metallopeptidase	-
ESP48_RS08350 (ESP48_08350)	ccpA	1546943..1547944 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
ESP48_RS08355 (ESP48_08355)	-	1548003..1548200 (+)	198	WP_014608125.1	hypothetical protein	-
ESP48_RS10295	-	1548306..1548530 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
ESP48_RS08360 (ESP48_08360)	-	1548531..1549070 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
ESP48_RS08365 (ESP48_08365)	-	1549083..1550198 (+)	1116	WP_011680937.1	glycerate kinase	-
ESP48_RS08370 (ESP48_08370)	-	1550245..1550700 (-)	456	WP_011680938.1	YueI family protein	-
ESP48_RS08375 (ESP48_08375)	eno	1550909..1552213 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
ESP48_RS08380 (ESP48_08380)	-	1552365..1552550 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=339202 ESP48_RS08350 WP_004197422.1 1546943..1547944(+) (ccpA) [Streptococcus thermophilus strain IDCC2201]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=339202 ESP48_RS08350 WP_004197422.1 1546943..1547944(+) (ccpA) [Streptococcus thermophilus strain IDCC2201]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547