Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ESP48_RS05465 Genome accession   NZ_CP035306
Coordinates   1014207..1015478 (+) Length   423 a.a.
NCBI ID   WP_064355734.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain IDCC2201     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1009207..1020478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ESP48_RS05435 (ESP48_05435) - 1009542..1009933 (-) 392 Protein_1016 LytTR family DNA-binding domain-containing protein -
  ESP48_RS05440 (ESP48_05440) - 1010157..1010462 (+) 306 WP_014621013.1 hypothetical protein -
  ESP48_RS05445 (ESP48_05445) mutL 1010514..1012457 (+) 1944 WP_011680601.1 DNA mismatch repair endonuclease MutL -
  ESP48_RS05450 (ESP48_05450) - 1012587..1012808 (+) 222 WP_011680602.1 hypothetical protein -
  ESP48_RS05455 (ESP48_05455) ruvA 1012960..1013550 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA -
  ESP48_RS05460 (ESP48_05460) - 1013557..1014111 (+) 555 WP_014621014.1 DNA-3-methyladenine glycosylase I -
  ESP48_RS05465 (ESP48_05465) cinA 1014207..1015478 (+) 1272 WP_064355734.1 competence/damage-inducible protein A Machinery gene
  ESP48_RS05470 (ESP48_05470) recA 1015514..1016653 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  ESP48_RS05475 (ESP48_05475) spx 1016830..1017228 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45894.34 Da        Isoelectric Point: 5.2053

>NTDB_id=339180 ESP48_RS05465 WP_064355734.1 1014207..1015478(+) (cinA) [Streptococcus thermophilus strain IDCC2201]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGGNENRLLSVLDQSSKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELIFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAVPLQNLTGLAVGGIITVEGVTYVVLPGPPSELKPM
VNQELIPALTENHTTLYSRVLRFFGVGESQLVTIIKDLIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADRKLDVLEEQ
IRSTKTLDGKSLSDLIYGYGESNSLAYEVFYLLKKYGKTITAAESLTAGLFQASVADFPGASQVFKGGFVTYSMEEKAKM
LGIPLSKLEEHGVVSHFTAEKMAEGARVKTDSDYGIALTGVAGPDALEGHQAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDNLI

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=339180 ESP48_RS05465 WP_064355734.1 1014207..1015478(+) (cinA) [Streptococcus thermophilus strain IDCC2201]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATTCTTACAGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
AAAACTAGCTGAATTAGGAATTGACGTGTATTTTCACACAGCGGTAGGAGGCAATGAAAACCGTCTACTTTCAGTCTTAG
ACCAGTCTAGTAAACGTAGCGATTTAGTCATACTCTGTGGAGGACTTGGCCCTACTGAGGATGACTTAACCAAACAAACA
TTGGCTAAGTTTTTAGGCAAAGAACTCATTTTTGATGAGGAGGCAAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACATACACGAACGCCTAATAATGAACGCCAAGCGCAAATTGTTGAGGGGGCTGTCCCCTTGCAAAATCTCACAGGTC
TGGCAGTTGGAGGAATTATTACTGTTGAAGGAGTGACCTATGTTGTCTTGCCTGGTCCGCCAAGTGAACTCAAACCTATG
GTGAACCAAGAGCTTATTCCAGCTCTCACAGAGAATCATACTACGCTTTATTCTAGAGTCCTAAGGTTTTTTGGTGTTGG
AGAAAGTCAATTGGTGACTATTATTAAAGATCTCATTGTTAACCAAACAGACCCAACCATTGCGCCCTATGCTAAAGTGG
GAGAAGTGACCCTTCGCTTATCAACAAAGGCATCGTCGCAAGAAGAAGCGGATCGAAAACTAGATGTTTTAGAAGAACAA
ATTCGTTCTACTAAAACTCTAGATGGAAAAAGCTTGTCTGATCTCATCTATGGATATGGAGAATCAAATAGCTTAGCTTA
TGAAGTGTTCTATTTGCTTAAGAAATATGGCAAAACTATTACTGCAGCTGAAAGTTTAACAGCTGGCTTATTTCAAGCTA
GTGTTGCTGATTTTCCTGGAGCTTCACAAGTATTCAAGGGTGGTTTTGTCACCTATAGCATGGAAGAAAAAGCTAAAATG
TTGGGTATTCCCTTATCTAAATTAGAAGAGCATGGTGTTGTTAGTCATTTTACAGCAGAAAAAATGGCTGAGGGTGCCCG
AGTTAAGACAGATAGTGATTACGGAATTGCGCTTACTGGAGTAGCAGGACCAGATGCTTTGGAAGGGCATCAAGCAGGTA
CAGTCTTTATTGGTATTGCCGATAGAAACCAAGTGCGATCAATTAAGGTTGTTATAGGTGGAAGAAGTCGATCTGATGTT
AGATATATCAGTACACTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGGACAACTTAATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.463

99.054

0.738
  cinA Streptococcus mitis NCTC 12261

73.27

99.054

0.726
  cinA Streptococcus pneumoniae TIGR4

72.076

99.054

0.714
  cinA Streptococcus pneumoniae R6

71.838

99.054

0.712
  cinA Streptococcus pneumoniae Rx1

71.838

99.054

0.712
  cinA Streptococcus pneumoniae D39

71.599

99.054

0.709
  cinA Streptococcus mutans UA159

69.976

100

0.7
  cinA Streptococcus suis isolate S10

54.327

98.345

0.534
  cinA Bacillus subtilis subsp. subtilis str. 168

44.418

99.527

0.442

Multiple sequence alignment