Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   ESP48_RS04345 Genome accession   NZ_CP035306
Coordinates   817124..817450 (-) Length   108 a.a.
NCBI ID   WP_002946126.1    Uniprot ID   A0A0E2Q1B3
Organism   Streptococcus thermophilus strain IDCC2201     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 812124..822450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ESP48_RS10105 (ESP48_04300) - 812389..812814 (-) 426 WP_014608739.1 CPBP family intramembrane glutamic endopeptidase -
  ESP48_RS10110 (ESP48_04305) - 812771..813046 (-) 276 WP_011681681.1 hypothetical protein -
  ESP48_RS04310 (ESP48_04310) - 813058..813256 (-) 199 Protein_823 helix-turn-helix transcriptional regulator -
  ESP48_RS04315 (ESP48_04315) - 813505..814698 (-) 1194 WP_014608740.1 acetate kinase -
  ESP48_RS04320 (ESP48_04320) comYH 814754..815710 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  ESP48_RS04325 (ESP48_04325) comGG 815755..816072 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG -
  ESP48_RS04330 (ESP48_04330) comYF 816050..816487 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  ESP48_RS04335 (ESP48_04335) comGE 816471..816764 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  ESP48_RS04340 (ESP48_04340) comYD 816736..817164 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  ESP48_RS04345 (ESP48_04345) comYC 817124..817450 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  ESP48_RS04350 (ESP48_04350) comYB 817447..818547 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  ESP48_RS04355 (ESP48_04355) comGA/cglA/cilD 818429..819370 (-) 942 WP_014608745.1 competence type IV pilus ATPase ComGA Machinery gene
  ESP48_RS04360 (ESP48_04360) - 819451..819813 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 11914.00 Da        Isoelectric Point: 9.9219

>NTDB_id=339174 ESP48_RS04345 WP_002946126.1 817124..817450(-) (comYC) [Streptococcus thermophilus strain IDCC2201]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=339174 ESP48_RS04345 WP_002946126.1 817124..817450(-) (comYC) [Streptococcus thermophilus strain IDCC2201]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2Q1B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus mutans UA140

69.231

96.296

0.667
  comYC Streptococcus mutans UA159

69.231

96.296

0.667
  comYC Streptococcus gordonii str. Challis substr. CH1

63.81

97.222

0.62
  comGC/cglC Streptococcus mitis SK321

62.264

98.148

0.611
  comGC/cglC Streptococcus mitis NCTC 12261

58.333

100

0.583
  comGC/cglC Streptococcus pneumoniae D39

58.491

98.148

0.574
  comGC/cglC Streptococcus pneumoniae R6

58.491

98.148

0.574
  comGC/cglC Streptococcus pneumoniae Rx1

58.491

98.148

0.574
  comGC/cglC Streptococcus pneumoniae TIGR4

58.491

98.148

0.574
  comGC Lactococcus lactis subsp. cremoris KW2

56.604

98.148

0.556
  comYC Streptococcus suis isolate S10

60.227

81.481

0.491
  comGC Staphylococcus aureus MW2

50

72.222

0.361
  comGC Staphylococcus aureus N315

50

72.222

0.361

Multiple sequence alignment