Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F1745_RS21015 Genome accession   NZ_CP043825
Coordinates   4239657..4240247 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain RM8082     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4234657..4245247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1745_RS21000 (F1745_21115) uhpT 4235179..4236570 (-) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -
  F1745_RS21005 (F1745_21120) uhpC 4236826..4238145 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  F1745_RS21010 (F1745_21125) uhpB 4238155..4239657 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  F1745_RS21015 (F1745_21130) letA 4239657..4240247 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  F1745_RS21020 (F1745_21135) ilvN 4240322..4240612 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  F1745_RS21025 (F1745_21140) ilvB 4240616..4242304 (-) 1689 WP_238013728.1 acetolactate synthase large subunit -
  F1745_RS21030 (F1745_21145) ivbL 4242410..4242508 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  F1745_RS21035 (F1745_21150) tisB 4243073..4243162 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  F1745_RS21040 ysdE 4243425..4243499 (-) 75 WP_211180519.1 protein YsdE -
  F1745_RS21045 (F1745_21155) emrD 4243581..4244765 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=339018 F1745_RS21015 WP_000633668.1 4239657..4240247(-) (letA) [Escherichia coli strain RM8082]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=339018 F1745_RS21015 WP_000633668.1 4239657..4240247(-) (letA) [Escherichia coli strain RM8082]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378