Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   F1745_RS18885 Genome accession   NZ_CP043825
Coordinates   3764978..3765610 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain RM8082     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3759978..3770610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1745_RS18860 (F1745_18965) yheS 3760144..3762057 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  F1745_RS18865 (F1745_18970) yheT 3762057..3763079 (+) 1023 WP_032142031.1 hydrolase -
  F1745_RS18870 (F1745_18975) yheU 3763073..3763291 (+) 219 WP_000907085.1 YheU family protein -
  F1745_RS18875 (F1745_18980) prkB 3763345..3764214 (+) 870 WP_001274680.1 phosphoribulokinase -
  F1745_RS18880 (F1745_18985) yhfA 3764269..3764673 (-) 405 WP_001148908.1 OsmC family protein -
  F1745_RS18885 (F1745_18990) crp 3764978..3765610 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  F1745_RS18890 (F1745_18995) yhfK 3765661..3767751 (+) 2091 WP_032142032.1 YccS/YhfK family putative transporter -
  F1745_RS18895 (F1745_19000) argD 3767818..3769038 (-) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  F1745_RS18900 (F1745_19005) pabA 3769124..3769687 (-) 564 WP_032142035.1 aminodeoxychorismate synthase component 2 -
  F1745_RS18905 (F1745_19010) fic 3769719..3770321 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  F1745_RS18910 (F1745_19015) yhfG 3770311..3770478 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=339010 F1745_RS18885 WP_000242755.1 3764978..3765610(+) (crp) [Escherichia coli strain RM8082]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=339010 F1745_RS18885 WP_000242755.1 3764978..3765610(+) (crp) [Escherichia coli strain RM8082]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTAACGGGCCGTATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment