Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   F1748_RS21380 Genome accession   NZ_CP043821
Coordinates   4325654..4326244 (-) Length   196 a.a.
NCBI ID   WP_089516099.1    Uniprot ID   -
Organism   Escherichia coli strain RM10740     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4320654..4331244
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1748_RS21365 (F1748_21495) uhpT 4321294..4322685 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  F1748_RS21370 (F1748_21500) uhpC 4322823..4324142 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  F1748_RS21375 (F1748_21505) uhpB 4324152..4325654 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  F1748_RS21380 (F1748_21510) letA 4325654..4326244 (-) 591 WP_089516099.1 transcriptional regulator UhpA Regulator
  F1748_RS21385 (F1748_21515) ilvN 4326318..4326608 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  F1748_RS21390 (F1748_21520) ilvB 4326612..4328300 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  F1748_RS21395 (F1748_21525) ivbL 4328406..4328504 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  F1748_RS21400 (F1748_21530) tisB 4329069..4329158 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  F1748_RS21405 ysdE 4329421..4329495 (-) 75 WP_211180519.1 protein YsdE -
  F1748_RS21410 (F1748_21535) emrD 4329577..4330761 (+) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20874.33 Da        Isoelectric Point: 5.9982

>NTDB_id=338939 F1748_RS21380 WP_089516099.1 4325654..4326244(-) (letA) [Escherichia coli strain RM10740]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERLVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=338939 F1748_RS21380 WP_089516099.1 4325654..4326244(-) (letA) [Escherichia coli strain RM10740]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCTGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCTAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38

100

0.388
  letA Legionella pneumophila strain ERS1305867

38

100

0.388
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378