Detailed information NTG0338719

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH15_RS09380
• Genome accession: NZ_CP035265
• Coordinates: 1823516..1824526 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901920
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1818516..1829526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH15_RS09360 (EQH15_09850)	-	1819817..1820110 (-)	294	WP_000977371.1	hypothetical protein	-
EQH15_RS09365 (EQH15_09855)	-	1820272..1820724 (+)	453	WP_000079148.1	universal stress protein	-
EQH15_RS09370 (EQH15_09860)	-	1820759..1822147 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
EQH15_RS09375 (EQH15_09865)	-	1822213..1823175 (+)	963	WP_001124778.1	asparaginase	-
EQH15_RS09380 (EQH15_09870)	ccpA	1823516..1824526 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH15_RS09385 (EQH15_09875)	-	1824951..1825550 (-)	600	WP_000866725.1	response regulator transcription factor	-
EQH15_RS09390 (EQH15_09880)	-	1825552..1826649 (-)	1098	WP_000893550.1	sensor histidine kinase	-
EQH15_RS09395 (EQH15_09885)	-	1826649..1827386 (-)	738	WP_000832842.1	ABC transporter permease	-
EQH15_RS09400 (EQH15_09890)	-	1827388..1828272 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
EQH15_RS09405 (EQH15_09895)	-	1828259..1828453 (-)	195	WP_000820182.1	hypothetical protein	-
EQH15_RS09410 (EQH15_09900)	-	1828450..1828656 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=338719 EQH15_RS09380 WP_000990607.1 1823516..1824526(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901920]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=338719 EQH15_RS09380 WP_000990607.1 1823516..1824526(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901920]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568