Detailed information NTG0338642

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH16_RS09655
• Genome accession: NZ_CP035264
• Coordinates: 1860110..1861120 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901921
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1855110..1866120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH16_RS09635 (EQH16_10120)	-	1856411..1856704 (-)	294	WP_000977371.1	hypothetical protein	-
EQH16_RS09640 (EQH16_10125)	-	1856866..1857318 (+)	453	WP_000079148.1	universal stress protein	-
EQH16_RS09645 (EQH16_10130)	-	1857353..1858741 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
EQH16_RS09650 (EQH16_10135)	-	1858807..1859769 (+)	963	WP_001124778.1	asparaginase	-
EQH16_RS09655 (EQH16_10140)	ccpA	1860110..1861120 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH16_RS09660 (EQH16_10145)	-	1861545..1862144 (-)	600	WP_000866725.1	response regulator transcription factor	-
EQH16_RS09665 (EQH16_10150)	-	1862146..1863243 (-)	1098	WP_000893550.1	sensor histidine kinase	-
EQH16_RS09670 (EQH16_10155)	-	1863243..1863980 (-)	738	WP_000832842.1	ABC transporter permease	-
EQH16_RS09675 (EQH16_10160)	-	1863982..1864866 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
EQH16_RS09680 (EQH16_10165)	-	1864853..1865047 (-)	195	WP_000820182.1	hypothetical protein	-
EQH16_RS09685 (EQH16_10170)	-	1865044..1865250 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=338642 EQH16_RS09655 WP_000990607.1 1860110..1861120(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901921]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=338642 EQH16_RS09655 WP_000990607.1 1860110..1861120(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901921]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568