Detailed information NTG0338607

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: F1537_RS09330
• Genome accession: NZ_CP043770
• Coordinates: 1822076..1822750 (+)
• Length: 224 a.a.
• NCBI ID: WP_005647998.1
• Uniprot ID: A0ABY1VSD0
• Organism: Haemophilus influenzae biotype aegyptius strain HE7/F1946
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1817076..1827750

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
F1537_RS09295 (F1537_09305)	rpmG	1817993..1818163 (-)	171	WP_005613503.1	50S ribosomal protein L33	-
F1537_RS09300 (F1537_09310)	rpmB	1818175..1818411 (-)	237	WP_005542826.1	50S ribosomal protein L28	-
F1537_RS09305 (F1537_09315)	radC	1818625..1819290 (-)	666	WP_013526173.1	DNA repair protein RadC	Machinery gene
F1537_RS09310 (F1537_09320)	coaBC	1819453..1820655 (+)	1203	WP_011272308.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
F1537_RS09315 (F1537_09325)	dut	1820703..1821158 (+)	456	WP_005631431.1	dUTP diphosphatase	-
F1537_RS09320 (F1537_09330)	slmA	1821162..1821818 (+)	657	WP_005648000.1	nucleoid occlusion factor SlmA	-
F1537_RS09325 (F1537_09335)	-	1821840..1822091 (+)	252	WP_005647999.1	YheU family protein	-
F1537_RS09330 (F1537_09340)	crp	1822076..1822750 (+)	675	WP_005647998.1	cAMP-activated global transcriptional regulator CRP	Regulator
F1537_RS09335 (F1537_09345)	rumB	1823115..1823549 (-)	435	Protein_1791	23S rRNA (uracil(747)-C(5))-methyltransferase	-
F1537_RS10245	-	1823594..1823761 (+)	168	WP_158305134.1	hypothetical protein	-
F1537_RS09340 (F1537_09350)	-	1824142..1824858 (-)	717	WP_013526172.1	S24 family peptidase	-
F1537_RS09345 (F1537_09355)	-	1825034..1825312 (+)	279	WP_041174962.1	helix-turn-helix domain-containing protein	-
F1537_RS09350 (F1537_09360)	-	1825356..1827341 (+)	1986	WP_013526171.1	Mu transposase C-terminal domain-containing protein	-
F1537_RS09355 (F1537_09365)	-	1827352..1827750 (+)	399	WP_032826358.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25151.85 Da
• Isoelectric Point: 6.8375

>NTDB_id=338607 F1537_RS09330 WP_005647998.1 1822076..1822750(+) (crp) [Haemophilus influenzae biotype aegyptius strain HE7/F1946]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide

• Length: 675 bp

>NTDB_id=338607 F1537_RS09330 WP_005647998.1 1822076..1822750(+) (crp) [Haemophilus influenzae biotype aegyptius strain HE7/F1946]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGA
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterProScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (36-124)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Haemophilus influenzae Rd KW20	100	100	1
crp	Vibrio cholerae strain A1552	75.49	91.071	0.687
crp	Acinetobacter baumannii D1279779	48.705	86.161	0.42