Detailed information NTG0338564

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH17_RS09215
• Genome accession: NZ_CP035263
• Coordinates: 1845766..1846776 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901922
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1840766..1851776

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH17_RS09190 (EQH17_09745)	-	1842112..1842405 (-)	294	WP_000977363.1	hypothetical protein	-
EQH17_RS09195 (EQH17_09750)	-	1842567..1843019 (+)	453	WP_000079148.1	universal stress protein	-
EQH17_RS09200 (EQH17_09755)	-	1843054..1844442 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
EQH17_RS09205 (EQH17_09760)	-	1844508..1845470 (+)	963	WP_001124777.1	asparaginase	-
EQH17_RS09210 (EQH17_09765)	-	1845499..1845702 (-)	204	WP_001813553.1	hypothetical protein	-
EQH17_RS09215 (EQH17_09770)	ccpA	1845766..1846776 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH17_RS09220 (EQH17_09775)	-	1847200..1847799 (-)	600	WP_000866698.1	response regulator transcription factor	-
EQH17_RS09225 (EQH17_09780)	-	1847800..1848897 (-)	1098	WP_000893537.1	sensor histidine kinase	-
EQH17_RS09230 (EQH17_09785)	-	1848897..1849634 (-)	738	WP_001809843.1	ABC transporter permease	-
EQH17_RS09235 (EQH17_09790)	-	1849636..1850520 (-)	885	WP_000219347.1	ABC transporter ATP-binding protein	-
EQH17_RS09240 (EQH17_09795)	-	1850507..1850701 (-)	195	WP_000820187.1	hypothetical protein	-
EQH17_RS09245 (EQH17_09800)	-	1850698..1850904 (-)	207	Protein_1833	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=338564 EQH17_RS09215 WP_000990607.1 1845766..1846776(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901922]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=338564 EQH17_RS09215 WP_000990607.1 1845766..1846776(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901922]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568