Detailed information NTG0338487

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH18_RS09275
• Genome accession: NZ_CP035262
• Coordinates: 1853097..1854107 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901923
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1848097..1859107

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH18_RS09250 (EQH18_09780)	-	1849443..1849736 (-)	294	WP_000977363.1	hypothetical protein	-
EQH18_RS09255 (EQH18_09785)	-	1849898..1850350 (+)	453	WP_000079148.1	universal stress protein	-
EQH18_RS09260 (EQH18_09790)	-	1850385..1851773 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
EQH18_RS09265 (EQH18_09795)	-	1851839..1852801 (+)	963	WP_001124777.1	asparaginase	-
EQH18_RS09270 (EQH18_09800)	-	1852830..1853033 (-)	204	WP_001813553.1	hypothetical protein	-
EQH18_RS09275 (EQH18_09805)	ccpA	1853097..1854107 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH18_RS09280 (EQH18_09810)	-	1854531..1855130 (-)	600	WP_000866698.1	response regulator transcription factor	-
EQH18_RS09285 (EQH18_09815)	-	1855131..1856228 (-)	1098	WP_000893537.1	sensor histidine kinase	-
EQH18_RS09290 (EQH18_09820)	-	1856228..1856965 (-)	738	WP_001809843.1	ABC transporter permease	-
EQH18_RS09295 (EQH18_09825)	-	1856967..1857851 (-)	885	WP_000219347.1	ABC transporter ATP-binding protein	-
EQH18_RS09300 (EQH18_09830)	-	1857838..1858032 (-)	195	WP_000820187.1	hypothetical protein	-
EQH18_RS09305 (EQH18_09835)	-	1858029..1858235 (-)	207	Protein_1845	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=338487 EQH18_RS09275 WP_000990607.1 1853097..1854107(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901923]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=338487 EQH18_RS09275 WP_000990607.1 1853097..1854107(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901923]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568