Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   EQH19_RS05740 Genome accession   NZ_CP035261
Coordinates   1154003..1155352 (-) Length   449 a.a.
NCBI ID   WP_001861620.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901924     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1149003..1160352
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH19_RS05715 (EQH19_06080) - 1150549..1151535 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  EQH19_RS05720 (EQH19_06085) - 1151783..1152556 (-) 774 WP_000731139.1 potassium channel family protein -
  EQH19_RS05725 (EQH19_06090) - 1152603..1152857 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE/ParE family toxin -
  EQH19_RS05730 (EQH19_06095) relB 1152859..1153101 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  EQH19_RS05735 (EQH19_06100) vicX 1153192..1154001 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  EQH19_RS05740 (EQH19_06105) micB 1154003..1155352 (-) 1350 WP_001861620.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EQH19_RS05745 (EQH19_06110) micA 1155345..1156049 (-) 705 WP_000722076.1 response regulator YycF Regulator
  EQH19_RS05750 (EQH19_06115) mutY 1156104..1157279 (-) 1176 WP_000886153.1 A/G-specific adenine glycosylase -
  EQH19_RS10775 - 1157376..1157501 (+) 126 WP_001818232.1 hypothetical protein -
  EQH19_RS05755 (EQH19_06120) - 1157607..1159277 (-) 1671 WP_000845284.1 formate--tetrahydrofolate ligase -
  EQH19_RS05760 (EQH19_06125) coaB 1159507..1160196 (+) 690 WP_000699495.1 phosphopantothenate--cysteine ligase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51726.44 Da        Isoelectric Point: 4.9706

>NTDB_id=338382 EQH19_RS05740 WP_001861620.1 1154003..1155352(-) (micB) [Streptococcus pneumoniae strain TVO_1901924]
MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQINQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILFYMTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
LLLDSQDINGEYLNLRIRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALC
ETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIW
MEIDTDKMTQVVDNILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=338382 EQH19_RS05740 WP_001861620.1 1154003..1155352(-) (micB) [Streptococcus pneumoniae strain TVO_1901924]
ATGCTTGATTTACTGAAACAAACCATTTTTACCAGAGATTTTATCTTTATCCTGATTTTGTTAGGTTTCATCCTTGTTGT
GACCCTCTTATTACTGGAAAATAGACGTGATAATATTCAGTTGAAGCAAATCAATCAAAAGGTTAAAGATTTGATTGCAG
GAGATTATTCCAAGGTTCTTGATATGCAAGGTGGGTCTGAAATCACCAATATTACCAATAATTTGAATGACTTGTCGGAG
GTTATTCGTCTCACTCAGGAAAATCTAGAACAAGAGAGTAAGAGGCTAAATAGTATTCTGTTTTATATGACAGATGGGGT
TCTTGCGACCAACCGTCGGGGTCAGATTATCATGATTAACGATACAGCCAAGAAGCAACTGGGGTTGGTTAAGGAAGATG
TTCTGAATAGAAGCATTTTGGAATTGCTCAAGATAGAAGAAAACTATGAATTGCGTGATTTGATTACCCAAAGTCCAGAA
TTGTTGCTAGATTCCCAAGATATCAATGGCGAATATTTGAACCTTCGAATTCGCTTTGCCTTGATACGTCGAGAGTCTGG
CTTTATTTCAGGTTTGGTGGCTGTTTTGCATGATACGACGGAGCAGGAGAAGGAAGAACGCGAACGAAGACTCTTTGTTT
CCAATGTTAGCCATGAGTTACGGACTCCTCTGACTAGCGTAAAATCCTATCTTGAAGCCTTGGATGAGGGGGCTTTGTGT
GAAACTGTAGCACCAGACTTTATCAAGGTTTCTCTTGATGAAACCAACCGTATGATGCGCATGGTGACGGATCTCCTCCA
TCTTTCACGTATTGATAATGCTACCAGTCATCTAGATGTGGAACTGATTAACTTCACTGCTTTTATTACCTTTATCCTCA
ATCGTTTTGACAAGATGAAAGGACAGGAAAAGGAAAAAAAATATGAGTTGGTGAGAGATTATCCCATCAATTCTATCTGG
ATGGAAATTGATACAGATAAGATGACGCAGGTTGTCGACAATATTTTAAATAATGCTATTAAGTATTCGCCAGATGGGGG
TAAAATCACTGTCAGAATGAAGACAACTGAAGACCAGATGATTTTATCCATTTCTGACCACGGTTTGGGGATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTCTATCGTGTGGATCGTGCTAGAAGTCGTGCACAAGGTGGTACAGGTCTAGGA
CTGTCTATCGCTAAAGAAATTATCAAACAACATAAGGGCTTTATTTGGGCCAAGAGTGAATACGGCAAGGGTTCAACCTT
TACCATTGTGCTTCCTTATGATAAGGATGCAGTGAAAGAAGAAGTATGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(98-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

99.555

100

0.996
  vicK Streptococcus mutans UA159

70.149

89.532

0.628

Multiple sequence alignment