Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   VCM66_RS12540 Genome accession   NC_012578
Coordinates   2719380..2720012 (+) Length   210 a.a.
NCBI ID   WP_000242749.1    Uniprot ID   A0A6G8D3R0
Organism   Vibrio cholerae M66-2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2714380..2725012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VCM66_RS12515 (VCM66_2528) - 2714446..2716362 (+) 1917 WP_000627678.1 ABC transporter ATP-binding protein -
  VCM66_RS12520 (VCM66_2529) - 2716363..2716848 (+) 486 WP_001278735.1 TIGR02444 family protein -
  VCM66_RS12525 (VCM66_2530) - 2716845..2717834 (+) 990 WP_000627574.1 hydrolase -
  VCM66_RS12530 (VCM66_2532) - 2717962..2718171 (+) 210 WP_000586562.1 YheU family protein -
  VCM66_RS12535 (VCM66_2533) - 2718268..2719137 (+) 870 WP_001274669.1 phosphoribulokinase -
  VCM66_RS12540 (VCM66_2534) crp 2719380..2720012 (+) 633 WP_000242749.1 cAMP-activated global transcriptional regulator CRP Regulator
  VCM66_RS12545 (VCM66_2535) - 2720091..2720882 (-) 792 WP_000189091.1 DUF1338 domain-containing protein -
  VCM66_RS12550 (VCM66_2536) astD 2721025..2722482 (-) 1458 WP_000150145.1 succinylglutamate-semialdehyde dehydrogenase -
  VCM66_RS12555 (VCM66_2537) astA 2722492..2723511 (-) 1020 WP_000962042.1 arginine N-succinyltransferase -
  VCM66_RS12560 (VCM66_2538) - 2723650..2724861 (-) 1212 WP_000215478.1 aspartate aminotransferase family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23635.45 Da        Isoelectric Point: 8.2784

>NTDB_id=33838 VCM66_RS12540 WP_000242749.1 2719380..2720012(+) (crp) [Vibrio cholerae M66-2]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHAGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERTAWVRAKTPCEVAEISFKKFRQLIQVNPDILMRLSGQMARRLQVTSQKVGDLAFLDVTGRIAQTLLNLARQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEEQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=33838 VCM66_RS12540 WP_000242749.1 2719380..2720012(+) (crp) [Vibrio cholerae M66-2]
ATGGTTCTAGGTAAACCTCAAACCGATCCAACACTAGAGTGGTTTCTTTCACATTGTCACATTCATAAGTACCCATCAAA
AAGCACACTGATCCACGCGGGTGAGAAAGCGGAAACGCTGTACTACATCGTAAAAGGTTCAGTTGCGGTACTGATCAAAG
ATGAAGAAGGTAAAGAGATGATTCTCTCTTACCTGAACCAAGGTGATTTTATCGGTGAGCTTGGCTTGTTTGAAGAAGGC
CAAGAGCGTACAGCTTGGGTTCGTGCTAAAACACCTTGTGAAGTGGCTGAAATCTCATTTAAGAAATTCCGTCAATTGAT
CCAAGTAAACCCAGATATCTTGATGCGCCTTTCAGGTCAAATGGCTCGTCGTCTGCAAGTGACCAGCCAGAAAGTTGGCG
ACCTTGCGTTCCTAGACGTAACTGGCCGTATCGCACAGACTCTGCTGAATCTTGCACGTCAGCCAGATGCGATGACTCAC
CCTGACGGTATGCAAATCAAGATCACTCGCCAAGAGATCGGTCAAATTGTTGGCTGTTCTCGCGAAACCGTTGGCCGCAT
CCTGAAGATGCTGGAAGAGCAGAACCTGATCTCTGCCCACGGTAAAACCATCGTGGTTTACGGCACTCGCTAA

Domains

Predicted by InterproScan.

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D3R0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

100

100

1
  crp Haemophilus influenzae Rd KW20

75.49

97.143

0.733
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment