Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CPH39_RS09755 Genome accession   NZ_CP043542
Coordinates   2034088..2034744 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain F2_81     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2029088..2039744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CPH39_RS09725 (CPH39_09860) dcyD 2029967..2030953 (+) 987 WP_001128214.1 D-cysteine desulfhydrase -
  CPH39_RS09730 (CPH39_09865) tcyL 2030968..2031636 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  CPH39_RS09735 (CPH39_09870) tcyN 2031633..2032385 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CPH39_RS09740 (CPH39_09875) sdiA 2032615..2033337 (+) 723 WP_053884505.1 transcriptional regulator SdiA -
  CPH39_RS09745 (CPH39_09880) yecF 2033405..2033629 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  CPH39_RS09750 (CPH39_09885) yecU 2033616..2033792 (-) 177 WP_000590344.1 protein YecU -
  CPH39_RS26820 (CPH39_09890) - 2033830..2033946 (-) 117 WP_001302039.1 hypothetical protein -
  CPH39_RS09755 (CPH39_09895) letA 2034088..2034744 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CPH39_RS09760 (CPH39_09900) uvrC 2034741..2036573 (+) 1833 WP_053884504.1 excinuclease ABC subunit UvrC Machinery gene
  CPH39_RS09765 (CPH39_09905) pgsA 2036630..2037178 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CPH39_RS09785 (CPH39_09925) yecA 2037828..2038493 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=338293 CPH39_RS09755 WP_000611328.1 2034088..2034744(+) (letA) [Escherichia coli strain F2_81]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=338293 CPH39_RS09755 WP_000611328.1 2034088..2034744(+) (letA) [Escherichia coli strain F2_81]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATTGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACAAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment