Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CPH39_RS01855 Genome accession   NZ_CP043542
Coordinates   419393..420025 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain F2_81     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 414393..425025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CPH39_RS01830 (CPH39_01850) yhfG 414525..414692 (+) 168 WP_089637304.1 YhfG family protein -
  CPH39_RS01835 (CPH39_01855) fic 414682..415284 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  CPH39_RS01840 (CPH39_01860) pabA 415316..415879 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  CPH39_RS01845 (CPH39_01865) argD 415965..417185 (+) 1221 WP_044866757.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CPH39_RS01850 (CPH39_01870) yhfK 417252..419342 (-) 2091 WP_001309001.1 YccS/YhfK family putative transporter -
  CPH39_RS01855 (CPH39_01875) crp 419393..420025 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CPH39_RS01860 (CPH39_01880) yhfA 420327..420731 (+) 405 WP_096220425.1 OsmC family protein -
  CPH39_RS01865 (CPH39_01885) prkB 420786..421655 (-) 870 WP_001274680.1 phosphoribulokinase -
  CPH39_RS01870 (CPH39_01890) yheU 421709..421927 (-) 219 WP_000907085.1 YheU family protein -
  CPH39_RS01875 (CPH39_01895) yheT 421921..422943 (-) 1023 WP_053883650.1 hydrolase -
  CPH39_RS01880 (CPH39_01900) yheS 422943..424856 (-) 1914 WP_053883648.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=338267 CPH39_RS01855 WP_000242755.1 419393..420025(-) (crp) [Escherichia coli strain F2_81]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=338267 CPH39_RS01855 WP_000242755.1 419393..420025(-) (crp) [Escherichia coli strain F2_81]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467