Detailed information NTG0338254

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH21_RS09235
• Genome accession: NZ_CP035259
• Coordinates: 1821306..1822316 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901926
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1816306..1827316

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH21_RS09210 (EQH21_09690)	-	1817652..1817945 (-)	294	WP_000977371.1	hypothetical protein	-
EQH21_RS09215 (EQH21_09695)	-	1818107..1818559 (+)	453	WP_000079148.1	universal stress protein	-
EQH21_RS09220 (EQH21_09700)	-	1818594..1819982 (-)	1389	WP_000453141.1	Cof-type HAD-IIB family hydrolase	-
EQH21_RS09225 (EQH21_09705)	-	1820048..1821010 (+)	963	WP_001124777.1	asparaginase	-
EQH21_RS09230 (EQH21_09710)	-	1821039..1821242 (-)	204	WP_001092033.1	hypothetical protein	-
EQH21_RS09235 (EQH21_09715)	ccpA	1821306..1822316 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH21_RS09240 (EQH21_09720)	-	1822741..1823340 (-)	600	WP_000866702.1	response regulator transcription factor	-
EQH21_RS09245 (EQH21_09725)	-	1823341..1824438 (-)	1098	WP_000893498.1	sensor histidine kinase	-
EQH21_RS09250 (EQH21_09730)	-	1824438..1825175 (-)	738	WP_000832916.1	ABC transporter permease	-
EQH21_RS09255 (EQH21_09735)	-	1825177..1826061 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
EQH21_RS09260 (EQH21_09740)	-	1826048..1826242 (-)	195	WP_000820189.1	hypothetical protein	-
EQH21_RS09265	-	1826239..1826445 (-)	207	Protein_1841	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=338254 EQH21_RS09235 WP_000990607.1 1821306..1822316(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901926]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=338254 EQH21_RS09235 WP_000990607.1 1821306..1822316(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901926]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568