Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   F0L19_RS18315 Genome accession   NZ_CP043539
Coordinates   3684039..3684671 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O157 strain Al Ain     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3679039..3689671
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F0L19_RS18290 (F0L19_18290) yhfG 3679171..3679338 (+) 168 WP_000736862.1 YhfG family protein -
  F0L19_RS18295 (F0L19_18295) fic 3679328..3679930 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  F0L19_RS18300 (F0L19_18300) pabA 3679962..3680525 (+) 564 WP_000601867.1 aminodeoxychorismate synthase component 2 -
  F0L19_RS18305 (F0L19_18305) argD 3680611..3681831 (+) 1221 WP_000963819.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  F0L19_RS18310 (F0L19_18310) yhfK 3681898..3683988 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  F0L19_RS18315 (F0L19_18315) crp 3684039..3684671 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  F0L19_RS18320 (F0L19_18320) yhfA 3684973..3685377 (+) 405 WP_001148908.1 OsmC family protein -
  F0L19_RS18325 (F0L19_18325) prkB 3685432..3686301 (-) 870 WP_001274677.1 phosphoribulokinase -
  F0L19_RS18330 (F0L19_18330) yheU 3686355..3686573 (-) 219 WP_000907085.1 YheU family protein -
  F0L19_RS18335 (F0L19_18335) yheT 3686567..3687589 (-) 1023 WP_000057377.1 hydrolase -
  F0L19_RS18340 (F0L19_18340) yheS 3687589..3689502 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=338231 F0L19_RS18315 WP_000242755.1 3684039..3684671(-) (crp) [Escherichia coli O157 strain Al Ain]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=338231 F0L19_RS18315 WP_000242755.1 3684039..3684671(-) (crp) [Escherichia coli O157 strain Al Ain]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCTGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467