Detailed information NTG0338178

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH22_RS09495
• Genome accession: NZ_CP035258
• Coordinates: 1860363..1861373 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901927
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1855363..1866373

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH22_RS09470 (EQH22_09965)	-	1856709..1857002 (-)	294	WP_000977371.1	hypothetical protein	-
EQH22_RS09475 (EQH22_09970)	-	1857164..1857616 (+)	453	WP_000079148.1	universal stress protein	-
EQH22_RS09480 (EQH22_09975)	-	1857651..1859039 (-)	1389	WP_000453141.1	Cof-type HAD-IIB family hydrolase	-
EQH22_RS09485 (EQH22_09980)	-	1859105..1860067 (+)	963	WP_001124777.1	asparaginase	-
EQH22_RS09490 (EQH22_09985)	-	1860096..1860299 (-)	204	WP_001092033.1	hypothetical protein	-
EQH22_RS09495 (EQH22_09990)	ccpA	1860363..1861373 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH22_RS09500 (EQH22_09995)	-	1861798..1862397 (-)	600	WP_000866702.1	response regulator transcription factor	-
EQH22_RS09505 (EQH22_10000)	-	1862398..1863495 (-)	1098	WP_000893498.1	sensor histidine kinase	-
EQH22_RS09510 (EQH22_10005)	-	1863495..1864232 (-)	738	WP_000832916.1	ABC transporter permease	-
EQH22_RS09515 (EQH22_10010)	-	1864234..1865118 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
EQH22_RS09520 (EQH22_10015)	-	1865105..1865299 (-)	195	WP_000820189.1	hypothetical protein	-
EQH22_RS09525	-	1865296..1865502 (-)	207	Protein_1895	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=338178 EQH22_RS09495 WP_000990607.1 1860363..1861373(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901927]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=338178 EQH22_RS09495 WP_000990607.1 1860363..1861373(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901927]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568