Detailed information NTG0338129

Bioinformatically predicted

Overview

• Name: uvrB
• Type: Machinery gene
• Locus tag: MGAS2221_RS05450
• Genome accession: NZ_CP043530
• Coordinates: 1070963..1072954 (-)
• Length: 663 a.a.
• NCBI ID: WP_002984194.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS2221
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1065963..1077954

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS2221_RS05425 (MGAS2221_1083)	dltD	1066253..1067503 (-)	1251	WP_002984219.1	D-alanyl-lipoteichoic acid biosynthesis protein DltD	-
MGAS2221_RS05430 (MGAS2221_1084)	dltC	1067496..1067735 (-)	240	WP_002984216.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-
MGAS2221_RS05435 (MGAS2221_1085)	dltB	1067753..1069009 (-)	1257	WP_010922392.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
MGAS2221_RS05440 (MGAS2221_1086)	dltA	1069006..1070544 (-)	1539	WP_002989572.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
MGAS2221_RS05445 (MGAS2221_1087)	-	1070556..1070699 (-)	144	WP_002984200.1	teichoic acid D-Ala incorporation-associated protein DltX	-
MGAS2221_RS05450 (MGAS2221_1088)	uvrB	1070963..1072954 (-)	1992	WP_002984194.1	excinuclease ABC subunit UvrB	Machinery gene
MGAS2221_RS05455 (MGAS2221_1089)	-	1073147..1075321 (+)	2175	WP_011285590.1	ABC transporter substrate-binding protein/permease	-
MGAS2221_RS05460 (MGAS2221_1090)	-	1075321..1076061 (+)	741	WP_002984187.1	amino acid ABC transporter ATP-binding protein	-
MGAS2221_RS05465 (MGAS2221_1091)	-	1076209..1076361 (-)	153	WP_003062002.1	hypothetical protein	-
MGAS2221_RS05470 (MGAS2221_1092)	-	1076358..1077737 (-)	1380	WP_011285591.1	PTS transporter subunit EIIC	-

Sequence

Protein

• Length: 663 a.a.
• Molecular weight: 75654.68 Da
• Isoelectric Point: 4.6420

>NTDB_id=338129 MGAS2221_RS05450 WP_002984194.1 1070963..1072954(-) (uvrB) [Streptococcus pyogenes strain MGAS2221]
MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
DSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTI
GEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDG
RSPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGEYEMSQTNTIIEQIIRPTGLLDPEIDVRSSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADK
MTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEA
AELLDFELAAQMRDLILELKLMD

Nucleotide

• Length: 1992 bp

>NTDB_id=338129 MGAS2221_RS05450 WP_002984194.1 1070963..1072954(-) (uvrB) [Streptococcus pyogenes strain MGAS2221]
ATGATTGATAAACGTGATGATAAACCATTTAAACTAAAATCAAAGTATAAACCGTCTGGTGATCAGCCACAAGCTATTGA
AAGCCTAGTTGATAATATCGAGGGCGGAGAAAAAGCTCAGATTCTCCTAGGTGCTACAGGAACGGGAAAAACATACACCA
TGAGCCAAGTAATTAGTAAAGTAAATAAACCTACCTTAGTGATAGCTCACAATAAAACCTTAGCAGGACAATTATATGGT
GAATTTAAAGAATTTTTTCCAGACAATGCTGTGGAATATTTTGTTTCCTATTATGATTACTACCAACCTGAAGCATATGT
CCCATCAAGCGACACCTATATCGAAAAAGATAGTTCAGTCAATGATGAAATCGATAAACTTCGCCATTCAGCCACCTCTT
CTTTACTTGAGCGTAACGATGTCATAGTGGTAGCTTCTGTATCTTGTATTTATGGACTAGGTTCGCCAAAAGAGTACGCA
GATTCAGCAGTCAGCCTACGTCCAGGTCAGGAGATATCACGTGACACTTTGCTAAATCAATTAGTAGATATTCAATTTGA
GCGTAATGATATTGATTTTCAACGCGGCTGTTTTCGTGTACGTGGCGATGTTGTTGAGGTCTTTCCAGCATCCAGGGATG
AACATGCTTTTCGGGTGGAATTTTTCGGGGATGAGATTGACCGTATATGTGAAATCGAAAGTTTAACTGGTAAAACTATT
GGAGAAGTTGACCATTTGGTTTTATTTCCAGCTACTCACTTTGTAACAAATGATGAGCATATGGAGCAATCAATAGCCAA
AATTCAAGCAGAGTTAGCAGAGCAGTTACAGTTATTTGAATCTGAAGGTAAACTACTAGAAGCACAGCGATTACGCCAAA
GAACGGAATATGATATTGAAATGTTACGTGAAATGGGCTATACTAGCGGAGTCGAAAACTATTCCCGTCATATGGATGGC
AGGTCACCAGGAGAACCTCCTTATACCTTGTTAGATTTCTTCCCAGAAGATTTTTTAATTATGATTGATGAAAGTCACAT
GACAATGGGACAAATCAAAGGCATGTATAATGGTGACCAAGCCAGAAAACAAATGCTAGTTGACTATGGTTTTCGATTGC
CATCAGCTCTTGATAATCGTCCCTTAAGACGCGAGGAATTTGAAAGTCATGTGCACCAAATTGTCTATGTTTCAGCAACG
CCTGGTGAATACGAAATGTCACAGACTAATACAATTATTGAGCAAATTATTCGTCCGACTGGGCTACTTGATCCTGAAAT
TGATGTAAGGTCAAGTATGGGGCAAATGGATGATTTGTTGGGAGAAATTAACCAGCGCGTAGCGCGCGATGAACGGACGT
TCATCACAACCTTAACTAAAAAAATGGCAGAAGATTTGACTGATTATCTAAAAGAGATGGGTGTCAAGGTCAAGTATATG
CACAGTGATATTAAAACCTTAGAGCGAACAGAAATTATTCGTGATTTACGACTTGGTGTTTTTGATGTCTTGATTGGAAT
CAATCTGCTCCGTGAAGGGATTGATGTGCCAGAAGTTAGTCTTGTAGCCATTTTGGATGCTGATAAAGAGGGTTTCCTCC
GTAATGAACGCGGCTTGATTCAGACCATCGGTAGAGCAGCTCGAAACGTAGATGGTCATGTCATTATGTATGCGGACAAG
ATGACAGATTCTATGCAGCGAGCTATTGACGAAACGGCTCGTCGTCGTGAGATTCAAATAGCATATAACAAAGCGCACGG
CATCGTTCCACAAACTATAAAAAAAGACATCAGAGGCCTTATTAGTATAAGTAAAACAAGCCACAATGATATATCAAAAG
AAGAGATGGATTATGAAAGTATGTCAAGAGGAGAACGAAAAGAAGCGATCAATGCTCTGCAAAAACAAATGCAAGAGGCA
GCTGAATTACTTGATTTCGAATTGGCAGCTCAAATGCGAGACTTGATTTTAGAACTTAAATTAATGGACTAG

Domains

Predicted by InterProScan.

• Ultra-violet resistance protein B (UvrB) (556-598)

• UvrB interaction domain (UvrB_inter) (164-254)

• Helicase conserved C-terminal domain (Helicase_C) (443-548)

• UvrB/uvrC motif (UVR) (627-660)

• Type III restriction enzyme, res subunit (ResIII) (17-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrB	Streptococcus pneumoniae R6	84.917	100	0.849
uvrB	Streptococcus pneumoniae D39	84.917	100	0.849
uvrB	Streptococcus pneumoniae TIGR4	84.766	100	0.848