Detailed information NTG0338101

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH23_RS09690
• Genome accession: NZ_CP035257
• Coordinates: 1902287..1903297 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901928
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1897287..1908297

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH23_RS09665 (EQH23_10265)	-	1898272..1898566 (-)	295	Protein_1915	hypothetical protein	-
EQH23_RS09670 (EQH23_10270)	-	1898728..1899180 (+)	453	WP_000079148.1	universal stress protein	-
EQH23_RS09675 (EQH23_10275)	-	1899215..1900603 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
EQH23_RS09680 (EQH23_10280)	-	1900669..1901631 (+)	963	WP_001124786.1	asparaginase	-
EQH23_RS09685 (EQH23_10285)	-	1901660..1902223 (-)	564	WP_061752785.1	hypothetical protein	-
EQH23_RS09690 (EQH23_10290)	ccpA	1902287..1903297 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH23_RS09695 (EQH23_10295)	-	1903722..1904321 (-)	600	WP_000866703.1	response regulator transcription factor	-
EQH23_RS09700 (EQH23_10300)	-	1904322..1905419 (-)	1098	WP_000893503.1	sensor histidine kinase	-
EQH23_RS09705 (EQH23_10305)	-	1905419..1906156 (-)	738	WP_000832916.1	ABC transporter permease	-
EQH23_RS09710 (EQH23_10310)	-	1906158..1907042 (-)	885	WP_000219359.1	ABC transporter ATP-binding protein	-
EQH23_RS09715 (EQH23_10315)	-	1907029..1907223 (-)	195	WP_000715302.1	hypothetical protein	-
EQH23_RS09720 (EQH23_10320)	-	1907220..1907426 (-)	207	Protein_1926	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=338101 EQH23_RS09690 WP_000990607.1 1902287..1903297(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901928]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=338101 EQH23_RS09690 WP_000990607.1 1902287..1903297(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901928]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568