Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   EQH23_RS07195 Genome accession   NZ_CP035257
Coordinates   1441976..1443934 (-) Length   652 a.a.
NCBI ID   WP_000748887.1    Uniprot ID   A0A0T8L942
Organism   Streptococcus pneumoniae strain TVO_1901928     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1436976..1448934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH23_RS07175 (EQH23_07610) - 1437696..1438862 (-) 1167 WP_000521373.1 MalY/PatB family protein -
  EQH23_RS07180 (EQH23_07615) - 1438870..1439964 (-) 1095 WP_000031958.1 cystathionine gamma-synthase -
  EQH23_RS07185 - 1440122..1440844 (-) 723 WP_001010369.1 ABC transporter ATP-binding protein -
  EQH23_RS07190 - 1440869..1441804 (-) 936 WP_000768992.1 ABC transporter ATP-binding protein -
  EQH23_RS07195 (EQH23_07625) amiA 1441976..1443934 (-) 1959 WP_000748887.1 peptide ABC transporter substrate-binding protein Regulator
  EQH23_RS07200 (EQH23_07635) - 1444138..1445760 (-) 1623 WP_000017793.1 polysaccharide biosynthesis protein -
  EQH23_RS07205 (EQH23_07640) - 1445866..1447311 (+) 1446 WP_000590304.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  EQH23_RS07210 (EQH23_07645) - 1447354..1447551 (-) 198 WP_000051196.1 CsbD family protein -
  EQH23_RS07215 (EQH23_07650) - 1447652..1448223 (-) 572 Protein_1448 DUF1803 domain-containing protein -
  EQH23_RS07220 (EQH23_07655) - 1448207..1448719 (-) 513 WP_000892252.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72547.90 Da        Isoelectric Point: 4.9412

>NTDB_id=338076 EQH23_RS07195 WP_000748887.1 1441976..1443934(-) (amiA) [Streptococcus pneumoniae strain TVO_1901928]
MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPSSLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSL
AEDWTVSQDGLTYTYKLRKDAKWFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWDAN
NVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTS
DIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINF
ADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDIQQLTSDEFDS
SGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKR
YEKYADIQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESN
KKAQEELAKHVK

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=338076 EQH23_RS07195 WP_000748887.1 1441976..1443934(-) (amiA) [Streptococcus pneumoniae strain TVO_1901928]
ATGAAAAAGTCTAAGAGCAAATATCTAACCTTGGCAGGTCTTGTCCTGGGTACAGGAGTTTTATTGAGCGCGTGTGGAAA
TTCTAGCACGGCGTCAAAAACCTACAACTATGTTTATTCAAGTGATCCATCTAGCTTGAACTATCTAGCAGAAAACCGCG
CAGCAACATCCGATATTGTTGCAAATTTGGTAGACGGGTTATTAGAAAATGACCAATATGGGAATATTATTCCATCATTA
GCAGAGGATTGGACTGTTTCTCAGGACGGTTTGACCTATACCTACAAACTTCGTAAGGATGCCAAGTGGTTTACTTCTGA
GGGAGAAGAATATGCGCCTGTAACTGCCCAGGATTTTGTGACAGGTTTGCAATATGCAGCTGATAAAAAATCAGAAGCCT
TGTATCTAGTGCAGGACTCTGTTGCTGGTTTGGATGACTATATCACTGGTAAAACAAGCGACTTTTCAACTGTCGGTGTC
AAGGCACTTGATGACCAAACGGTTCAATATACTTTGGTTAAACCAGAACTTTACTGGAATTCAAAAACACTTGCAACGAT
ACTTTTTCCTGTTAATGCAGATTTCCTGAAATCAAAAGGGGATGATTTTGGGAAGGCGGATCCATCTAGTATTTTGTACA
ATGGACCTTTCTTGATGAAAGCACTTGTCTCAAAATCTGCTATTGAATATAAGAAAAACCCTAATTACTGGGATGCTAAT
AATGTCTTTGTAGACGATGTGAAATTGACCTACTATGATGGTAGCGACCAAGAATCACTGGAACGTAATTTTACAGCTGG
TGCTTATACTACGGCTCGTCTTTTTCCTAACAGCTCCAGCTATGAAGGGATTAAAGAAAAATACAAAAACAATATCATCT
ATAGTATGCAAAATTCAACTTCATATTTCTTTAATTTTAACCTAGATAGGAAGTCTTACAATTATACTTCTAAAACAAGT
GACATTGAAAAGAAATCGACCCAGGAAGCAGTTCTCAATAAAAACTTCCGTCAGGCTATCAATTTTGCTTTTGACAGAAC
ATCTTATGGGGCTCAGTCTGAAGGGAAAGAAGGTGCAACAAAGATTTTGCGTAACCTAGTGGTTCCTCCAAACTTTGTCA
GTATCAAGGGAAAAGACTTTGGTGAAGTTGTAGCCTCTAAGATGGTCAACTATGGTAAGGAATGGCAAGGTATCAACTTT
GCGGATGGTCAAGACCCTTACTACAATCCTGAGAAAGCCAAGGCTAAGTTTGCGGAAGCTAAGAAAGAACTCGAAGCAAA
GGGTGTTCAATTCCCAATCCACTTGGATAAGACTGTGGAAGTAACAGATAAAGTAGGCATACAAGGAGTTAGTTCTATCA
AACAATCAATTGAATCTGTTTTAGGTTCTGATAATGTAGTGATTGACATTCAGCAATTAACATCAGATGAGTTTGACAGT
TCAGGCTACTTTGCTCAAACAGCTGCTCAGAAAGACTATGATTTATATCATGGCGGTTGGGGACCTGATTATCAAGACCC
GTCAACCTATCTCGATATTTTTAATACTAATAGTGGAGGATTTCTGCAAAATCTTGGACTAGAGCCTGGTGAGGCCAATG
ACAAGGCTAAGGCAGTTGGACTGGATGTCTATACTCAAATGTTGGAAGAAGCTAATAAAGAGCAAGATCCAGCCAAACGT
TATGAGAAATATGCTGATATTCAAGCTTGGTTGATTGATAGTTCTTTAGTTCTTCCAAGTGTTTCGCGTGGGGGAACACC
ATCATTGAGAAGAACCGTACCATTTGCTGCTGCCTATGGTTTAACCGGTACAAAAGGGGTTGAATCATATAAATACCTCA
AAGTACAAGATAAGATTGTCACAACAGACGAATATGCAAAAGCCAGAGAAAAATGGTTGAAAGAAAAAGAAGAATCCAAT
AAAAAAGCCCAAGAAGAATTGGCAAAACATGTCAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(76-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8L942

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

56.269

100

0.564
  amiA3 Streptococcus thermophilus LMD-9

55.725

100

0.56
  amiA3 Streptococcus thermophilus LMG 18311

55.573

100

0.558

Multiple sequence alignment