Detailed information NTG0337947

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH26_RS09840
• Genome accession: NZ_CP035254
• Coordinates: 1924350..1925360 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901932
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1919350..1930360

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH26_RS09815 (EQH26_10350)	-	1920515..1920808 (-)	294	WP_000977368.1	hypothetical protein	-
EQH26_RS09820 (EQH26_10355)	-	1920970..1921422 (+)	453	WP_000079148.1	universal stress protein	-
EQH26_RS09825 (EQH26_10360)	-	1921457..1922845 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
EQH26_RS09830 (EQH26_10365)	-	1922911..1923873 (+)	963	WP_001124777.1	asparaginase	-
EQH26_RS09835 (EQH26_10370)	-	1923870..1924286 (-)	417	WP_001092032.1	hypothetical protein	-
EQH26_RS09840 (EQH26_10375)	ccpA	1924350..1925360 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH26_RS09845 (EQH26_10380)	-	1925785..1926384 (-)	600	WP_000866720.1	response regulator transcription factor	-
EQH26_RS09850 (EQH26_10385)	-	1926386..1927483 (-)	1098	WP_000893539.1	sensor histidine kinase	-
EQH26_RS09855 (EQH26_10390)	-	1927483..1928220 (-)	738	WP_000832837.1	ABC transporter permease	-
EQH26_RS09860 (EQH26_10395)	-	1928222..1929106 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
EQH26_RS09865 (EQH26_10400)	-	1929093..1929287 (-)	195	WP_000820185.1	hypothetical protein	-
EQH26_RS09870 (EQH26_10405)	-	1929284..1929490 (-)	207	WP_000503440.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=337947 EQH26_RS09840 WP_000990607.1 1924350..1925360(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901932]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=337947 EQH26_RS09840 WP_000990607.1 1924350..1925360(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901932]
ATGAATGCAGATGATACAGTAACCATTTATGATGTTGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGCTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568