Detailed information NTG0337934

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH26_RS09185
• Genome accession: NZ_CP035254
• Coordinates: 1811989..1812450 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250542.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901932
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1806989..1817450

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH26_RS09155 (EQH26_09660)	-	1807293..1808117 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH26_RS09160 (EQH26_09665)	rnpA	1808092..1808463 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH26_RS10875	-	1808480..1808611 (-)	132	WP_000768904.1	hypothetical protein	-
EQH26_RS09165 (EQH26_09670)	-	1808612..1809802 (-)	1191	WP_000167766.1	acetate kinase	-
EQH26_RS09170 (EQH26_09675)	comYH	1809853..1810806 (-)	954	WP_000345101.1	class I SAM-dependent methyltransferase	Machinery gene
EQH26_RS09175 (EQH26_09680)	-	1810867..1811461 (-)	595	Protein_1820	class I SAM-dependent methyltransferase	-
EQH26_RS09180 (EQH26_09685)	comGG/cglG	1811598..1812011 (-)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH26_RS09185 (EQH26_09690)	comGF/cglF	1811989..1812450 (-)	462	WP_000250542.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH26_RS09190 (EQH26_09695)	comGE/cglE	1812413..1812715 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH26_RS09195 (EQH26_09700)	comGD/cglD	1812678..1813082 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH26_RS09200 (EQH26_09705)	comGC/cglC	1813075..1813401 (-)	327	WP_000738636.1	comG operon protein ComGC	Machinery gene
EQH26_RS09205 (EQH26_09710)	comGB/cglB	1813403..1814419 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH26_RS09210 (EQH26_09715)	comGA/cglA/cilD	1814367..1815308 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH26_RS09215 (EQH26_09720)	-	1815384..1815749 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH26_RS09220 (EQH26_09725)	-	1815900..1816958 (-)	1059	WP_000649470.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17918.53 Da
• Isoelectric Point: 9.3137

>NTDB_id=337934 EQH26_RS09185 WP_000250542.1 1811989..1812450(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901932]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=337934 EQH26_RS09185 WP_000250542.1 1811989..1812450(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901932]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae D39	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae R6	96.078	100	0.961
comGF/cglF	Streptococcus pneumoniae TIGR4	96.078	100	0.961
comGF/cglF	Streptococcus mitis SK321	92.157	100	0.922
comGF/cglF	Streptococcus mitis NCTC 12261	90.85	100	0.909