Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FQT94_RS19035 Genome accession   NZ_CP043486
Coordinates   3943620..3944210 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain SL112     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3938620..3949210
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FQT94_RS19020 (FQT94_19345) uhpT 3939260..3940651 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  FQT94_RS19025 (FQT94_19350) uhpC 3940789..3942108 (-) 1320 WP_000936565.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FQT94_RS19030 (FQT94_19355) uhpB 3942118..3943620 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FQT94_RS19035 (FQT94_19360) letA 3943620..3944210 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FQT94_RS19040 (FQT94_19365) ilvN 3944285..3944575 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  FQT94_RS19045 (FQT94_19370) ilvB 3944579..3946267 (-) 1689 WP_000168480.1 acetolactate synthase large subunit -
  FQT94_RS19050 (FQT94_19375) ivbL 3946373..3946471 (-) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  FQT94_RS19055 (FQT94_19380) tisB 3947036..3947125 (+) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  FQT94_RS23305 ysdE 3947388..3947462 (-) 75 WP_211180519.1 protein YsdE -
  FQT94_RS19060 (FQT94_19385) emrD 3947544..3948728 (+) 1185 WP_001349998.1 multidrug efflux MFS transporter EmrD -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=337901 FQT94_RS19035 WP_000633668.1 3943620..3944210(-) (letA) [Escherichia coli strain SL112]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=337901 FQT94_RS19035 WP_000633668.1 3943620..3944210(-) (letA) [Escherichia coli strain SL112]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCTCTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCTACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378