Detailed information NTG0337864

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH28_RS10105
• Genome accession: NZ_CP035252
• Coordinates: 1959076..1959537 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901934
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1954076..1964537

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH28_RS10075 (EQH28_10635)	-	1954383..1955207 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH28_RS10080 (EQH28_10640)	rnpA	1955182..1955553 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH28_RS11245	-	1955570..1955701 (-)	132	WP_000768904.1	hypothetical protein	-
EQH28_RS10085 (EQH28_10645)	-	1955702..1956892 (-)	1191	WP_000167765.1	acetate kinase	-
EQH28_RS10090 (EQH28_10650)	comYH	1956943..1957896 (-)	954	WP_000345126.1	class I SAM-dependent methyltransferase	Machinery gene
EQH28_RS10095 (EQH28_10655)	-	1957957..1958549 (-)	593	Protein_1985	class I SAM-dependent methyltransferase	-
EQH28_RS10100 (EQH28_10660)	comGG/cglG	1958652..1959098 (-)	447	WP_061751327.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH28_RS10105 (EQH28_10665)	comGF/cglF	1959076..1959537 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH28_RS10110 (EQH28_10670)	comGE/cglE	1959500..1959802 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH28_RS10115 (EQH28_10675)	comGD/cglD	1959765..1960199 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH28_RS10120 (EQH28_10680)	comGC/cglC	1960162..1960485 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
EQH28_RS10125 (EQH28_10685)	comGB/cglB	1960487..1961503 (-)	1017	WP_078130737.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH28_RS10130 (EQH28_10690)	comGA/cglA/cilD	1961451..1962392 (-)	942	WP_000249536.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH28_RS10135 (EQH28_10695)	-	1962468..1962833 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH28_RS10140 (EQH28_10700)	-	1962984..1964042 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=337864 EQH28_RS10105 WP_000250531.1 1959076..1959537(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901934]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=337864 EQH28_RS10105 WP_000250531.1 1959076..1959537(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901934]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915