Detailed information NTG0337859

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH28_RS09805
• Genome accession: NZ_CP035252
• Coordinates: 1910233..1911243 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901934
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1905233..1916243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH28_RS09780 (EQH28_10340)	-	1905298..1906512 (-)	1215	WP_047475499.1	pyridoxal phosphate-dependent aminotransferase	-
EQH28_RS09785 (EQH28_10345)	-	1906668..1906962 (-)	295	Protein_1936	hypothetical protein	-
EQH28_RS09790 (EQH28_10350)	-	1907124..1907576 (+)	453	WP_000079148.1	universal stress protein	-
EQH28_RS09795 (EQH28_10355)	-	1907611..1908999 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
EQH28_RS09800 (EQH28_10360)	-	1909065..1910027 (+)	963	WP_001124777.1	asparaginase	-
EQH28_RS09805 (EQH28_10365)	ccpA	1910233..1911243 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH28_RS09810 (EQH28_10370)	-	1911668..1912267 (-)	600	WP_000866719.1	response regulator transcription factor	-
EQH28_RS09815 (EQH28_10375)	-	1912269..1913366 (-)	1098	WP_000893546.1	sensor histidine kinase	-
EQH28_RS09820 (EQH28_10380)	-	1913366..1914103 (-)	738	WP_061751287.1	ABC transporter permease	-
EQH28_RS09825 (EQH28_10385)	-	1914105..1914989 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
EQH28_RS09830 (EQH28_10390)	-	1914976..1915170 (-)	195	WP_000820180.1	hypothetical protein	-
EQH28_RS09835 (EQH28_10395)	-	1915167..1915373 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=337859 EQH28_RS09805 WP_000990607.1 1910233..1911243(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901934]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=337859 EQH28_RS09805 WP_000990607.1 1910233..1911243(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901934]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568