Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   SOR_RS08845 Genome accession   NC_015291
Coordinates   1774194..1776143 (-) Length   649 a.a.
NCBI ID   WP_000018202.1    Uniprot ID   -
Organism   Streptococcus oralis Uo5     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1769194..1781143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS08815 (SOR_1808) - 1769486..1770520 (+) 1035 WP_000255139.1 S66 peptidase family protein -
  SOR_RS08820 (SOR_1809) - 1770626..1770889 (+) 264 WP_000166112.1 SemiSWEET family transporter -
  SOR_RS08825 (SOR_1810) - 1770970..1771536 (-) 567 WP_001126061.1 DNA-3-methyladenine glycosylase I -
  SOR_RS08830 (SOR_1811) ruvA 1771546..1772139 (-) 594 WP_000273401.1 Holliday junction branch migration protein RuvA Machinery gene
  SOR_RS08835 (SOR_1812) - 1772152..1773384 (-) 1233 WP_000657470.1 MFS transporter -
  SOR_RS08840 (SOR_1813) - 1773556..1774053 (+) 498 WP_000761365.1 helix-turn-helix domain-containing protein -
  SOR_RS08845 (SOR_1814) hexB 1774194..1776143 (-) 1950 WP_000018202.1 DNA mismatch repair endonuclease MutL Machinery gene
  SOR_RS08850 (SOR_1816) - 1776457..1776897 (+) 441 WP_000861945.1 LytTR family DNA-binding domain-containing protein -
  SOR_RS08855 (SOR_1817) - 1776894..1777352 (+) 459 WP_000743967.1 DUF3021 domain-containing protein -
  SOR_RS08860 (SOR_1818) hexA 1777394..1779928 (-) 2535 WP_000179927.1 DNA mismatch repair protein MutS Machinery gene
  SOR_RS08865 (SOR_1819) argR 1779979..1780425 (-) 447 WP_001231483.1 arginine repressor -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73404.89 Da        Isoelectric Point: 5.5321

>NTDB_id=33758 SOR_RS08845 WP_000018202.1 1774194..1776143(-) (hexB) [Streptococcus oralis Uo5]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGQVEEVIPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSAKKMIEIENSDLDFEITGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKERELMALLSE
AISNSLKEQALIPDALENLAKSTVRNRQKVEQTILPLKENTLYYEKTELSKPSQAEVADHQVELTEEGRDLTLFAKETLD
QLTKPAKLHFAERKPANYDQLDHPELDLASLDKAYDKLEREESSSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=33758 SOR_RS08845 WP_000018202.1 1774194..1776143(-) (hexB) [Streptococcus oralis Uo5]
ATGTCTCATATTATTGAATTGCCAGAAGTGTTAGCAAACCAGATCGCGGCAGGGGAGGTTATCGAACGTCCTGCCAGTGT
GGTCAAAGAGTTGGTAGAAAATGCCATTGACGCGGGTTCTAGCCAGATTATCATTGAGATTGAGGAAGCTGGTCTCAAGA
AAATTCAAATCACCGATAATGGTCATGGAATTGCCCACGATGAGGTGGAGTTGGCCTTGCGTCGCCATGCGACCAGTAAG
ATAAAAAATCAGGCAGACCTCTTTCGGATTCGGACGCTTGGTTTTCGTGGTGAAGCCCTGCCTTCTATCGCTTCTGTCAG
TGTGCTGACTCTGTTGACGGCGGTGGATGGTGCGAGTCATGGGACTAAGTTAGTCGCGCGTGGAGGTCAAGTTGAGGAAG
TCATCCCAGCGACTAGCCCTGTAGGAACCAAAGTTTGTGTGGAAGACCTCTTTTTCAACACACCTGCCCGTCTCAAGTAT
ATGAAGAGCCAGCAAGCGGAGCTGTCTCATATCATTGATATTGTCAACCGTCTGGGCTTGGCTCATCCCGAGATTTCTTT
TAGTTTAATCAGTGATGGCAAGGAAATGACGCGGACAGCAGGGACTGGTCAACTGCGTCAAGCCATCGCAGGGATTTACG
GTTTGGTGAGTGCTAAGAAGATGATTGAAATTGAGAACTCTGACTTAGATTTCGAAATTACAGGTTTTGTGTCTCTGCCT
GAGTTAACCCGAGCAAATCGCAACTATATCAGCCTCTTCATCAATGGCCGTTATATCAAGAACTTTCTACTCAACCGTGC
TATTCTTGACGGTTATGGAAGCAAGCTCATGGTAGGGCGTTTTCCACTGGCTGTCATTCACATCCATATTGATCCTTATT
TGGCAGATGTCAATGTGCATCCGACCAAGCAAGAAGTGCGGATTTCTAAGGAAAGAGAACTGATGGCGCTGCTTTCAGAG
GCTATTTCAAATAGTCTCAAGGAGCAAGCCTTGATTCCTGATGCTTTAGAAAATCTTGCCAAGTCGACCGTGCGCAATCG
TCAAAAGGTAGAGCAGACCATTCTCCCACTCAAAGAAAATACGCTTTACTATGAAAAAACAGAACTCTCAAAACCTAGTC
AAGCTGAGGTGGCTGACCACCAGGTTGAATTAACTGAGGAGGGTAGGGACCTAACCCTGTTTGCTAAAGAAACTTTGGAC
CAATTGACTAAGCCAGCAAAACTGCATTTTGCAGAGAGAAAGCCTGCTAACTATGACCAATTGGACCATCCAGAGTTAGA
TCTTGCTAGCCTCGATAAGGCTTATGACAAGCTGGAGCGAGAAGAATCATCCAGCTTCCCAGAGTTGGAGTTTTTCGGAC
AAATGCACGGGACCTATCTTTTTGCCCAAGGGCGAGATGGCCTCTACATCATAGACCAGCACGCGGCCCAGGAACGAGTT
AAGTACGAGGAATACCGTGAAAGCATCGGCAATGTTGACCAGAGCCAGCAGCAACTCCTAGTGCCCTACATCTTTGAATT
TCCTGCGGATGATGCGCTTCGTCTCAAGGAAAGAATGCCTCTCTTAGAGGAAGTGGGTGTCTTTTTAGCAGAGTACGGAG
AAAATCAATTTATCCTACGTGAACATCCTATTTGGATGGCAGAAGAAGAGATTGAATCAGGCATCTATGAGATGTGCGAC
ATGCTCCTTTTGACCAAGGAAGTTTCTATCAAGAAATACCGAGCAGAGCTGGCTATCATGATGTCCTGCAAGCGGTCTAT
CAAGGCAAACCATCGCATCGATGACCACTCAGCCAGACAACTCCTCTATCAGCTCTCTCAATGCGACAATCCCTATAACT
GTCCCCACGGACGTCCCGTTTTGGTGCATTTCACCAAGTCGGATATGGAAAAAATGTTCCGACGCATTCAGGAAAATCAT
ACTAGCCTCCGTGAGTTGGGGAAATATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)

MutL C terminal dimerisation domain (MutL_C)

(450-592)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

96.918

100

0.969