Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   SOR_RS08860 Genome accession   NC_015291
Coordinates   1777394..1779928 (-) Length   844 a.a.
NCBI ID   WP_000179927.1    Uniprot ID   -
Organism   Streptococcus oralis Uo5     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1772394..1784928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS08840 (SOR_1813) - 1773556..1774053 (+) 498 WP_000761365.1 helix-turn-helix domain-containing protein -
  SOR_RS08845 (SOR_1814) hexB 1774194..1776143 (-) 1950 WP_000018202.1 DNA mismatch repair endonuclease MutL Machinery gene
  SOR_RS08850 (SOR_1816) - 1776457..1776897 (+) 441 WP_000861945.1 LytTR family DNA-binding domain-containing protein -
  SOR_RS08855 (SOR_1817) - 1776894..1777352 (+) 459 WP_000743967.1 DUF3021 domain-containing protein -
  SOR_RS08860 (SOR_1818) hexA 1777394..1779928 (-) 2535 WP_000179927.1 DNA mismatch repair protein MutS Machinery gene
  SOR_RS08865 (SOR_1819) argR 1779979..1780425 (-) 447 WP_001231483.1 arginine repressor -
  SOR_RS08870 (SOR_1820) argS 1780580..1782271 (+) 1692 WP_001092715.1 arginine--tRNA ligase -
  SOR_RS08875 (SOR_1821) - 1782840..1783085 (+) 246 WP_000084867.1 hypothetical protein -
  SOR_RS08880 (SOR_1822) - 1783284..1784546 (+) 1263 WP_000084701.1 NRAMP family divalent metal transporter -

Sequence

Protein


Download         Length: 844 a.a.        Molecular weight: 94669.00 Da        Isoelectric Point: 4.8313

>NTDB_id=33759 SOR_RS08860 WP_000179927.1 1777394..1779928(-) (hexA) [Streptococcus oralis Uo5]
MATEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAINAAQILEISLTSRNKNAENPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDRDGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKEGFEDLHLLDSRLADVEQAAASKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKTSLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKKRIVQRQDVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIEQLDAIPELESLISAAIAP
EAPHVITEGGIIRTGFDETLDKYRRVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPSHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVSKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
EDSQIDIQKGRHAVVEKVMGAQTYIPNSIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKDSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLEHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPAELLARADKILTQLESQGGESPAPMSQTSA
VTEQMSLFDAPEEHPILAELAKLDVYNMTPMQAMNVLVELKQKL

Nucleotide


Download         Length: 2535 bp        

>NTDB_id=33759 SOR_RS08860 WP_000179927.1 1777394..1779928(-) (hexA) [Streptococcus oralis Uo5]
ATGGCAACAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAGAAACAATACCCAGATGCTTTTTTGCTTTT
TCGGATGGGTGATTTTTACGAGTTGTTCTATGAAGATGCAATTAATGCAGCACAGATTTTAGAAATTTCCTTAACGAGTC
GGAATAAAAATGCAGAAAATCCGATACCCATGGCGGGTGTCCCCTATCATTCTGCCCAACAGTATATCGATGTTCTGATT
GAGCAGGGCTATAAGGTGGCCATTGCCGAACAGATGGAAGATCCTAAACAAGCAGTTGGGGTTGTCAAGCGTGAGGTGGT
CCAGGTCATCACACCTGGAACGGTCGTCGATAGCAGTAAGCCGGATAGTCAGAATAATTTTTTGGTTGCCTTAGATCGCG
ATGGCAATCAGTTTGGTCTGGCTTATATGGACCTAGTGACGGGTGACTTCTATGTGACAGGTCTATTAGATTTTACGTTG
GTTTGTGGGGAAATTCGCAACCTCAAGGCTCGAGAAGTGGTGCTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATCCT
CAGCCGTCAGATGAATCTGGTACTTTCTTATGAAAAAGAAGGCTTTGAGGACCTTCATTTACTGGATTCACGACTGGCAG
ATGTGGAGCAAGCAGCAGCTAGTAAGCTCCTCCAGTATGTTCACCGGACCCAGATGAGGGAGTTGAACCACCTCAAACCT
GTTATCCGCTATGAAATCAAAGATTTCTTGCAGATGGATTATGCGACCAAGACTAGTTTGGATTTGGTTGAGAATGCCCG
GTCAGGTAAGAAGCAAGGCAGTCTTTTCTGGCTTTTAGATGAAACCAAAACGGCTATGGGTATGCGGCTCTTACGTTCTT
GGATTCATCGTCCTTTGATTGATAAGAAGCGAATTGTCCAACGTCAAGACGTGGTGCAGGTCTTTCTTGACCACTTCTTT
GAGCGTAGTGATTTGACAGACAGTCTCAAGGGGGTTTATGACATCGAACGTTTGGCTAGTCGGGTTTCTTTTGGCAAGAC
CAATCCCAAGGATCTCTTGCAGTTGGCGACCACCTTATCCAGTGTACCACGGATTCGTGCGATTTTAGAAGGCATGGAGC
AACCTGCCCTGGCCTATCTTATCGAACAGTTAGATGCCATCCCTGAGTTGGAGAGCTTGATTAGTGCTGCCATTGCTCCT
GAAGCTCCTCACGTGATTACGGAAGGTGGCATTATCCGTACGGGATTTGATGAGACCTTAGACAAGTACCGTCGTGTGCT
CAGAGAAGGTACCAGCTGGATTGCAGAGATTGAGGCTAAGGAGAGAGAAAACTCTGGCATCAGTACGCTTAAGATTGACT
ACAATAAAAAGGACGGTTACTATTTCCATGTGACCAATTCGCAACTGGGAAATGTGCCATCCCACTTTTTCCGCAAGGCA
ACACTGAAAAACTCAGAACGCTTTGGTACCGAAGAATTGGCCCGTATCGAGGGAGATATGCTGGAGGCGCGTGAGAAGTC
AGCCAACCTAGAATATGAAATCTTTATGCGCATCCGTGAGGAAGTCAGCAAGTACATCCAGCGTTTGCAAGCGCTAGCCC
AAGGAATTGCGACAGTTGATGTCTTGCAAAGTCTAGCAGTTGTAGCTGAAACCCAGCATTTGATCAGACCTGAGTTTGGA
GAGGATTCACAAATAGATATCCAAAAAGGGCGCCATGCTGTCGTCGAAAAGGTCATGGGAGCTCAGACCTACATTCCAAA
CAGTATCCAGATGGCAGAAGATACCAGTATTCAGCTAATCACAGGGCCTAACATGAGCGGGAAGTCAACCTACATGCGCC
AGTTAGCCATGACGGCGGTGATGGCCCAGCTGGGTTCTTATGTGCCGGCAGAAAGCGCCCATTTGCCTATCTTCGATGCT
ATCTTTACCCGTATCGGAGCAGCAGATGACTTGGTTTCAGGTCAATCAACCTTTATGGTGGAGATGATGGAGGCCAACAA
TGCCATTTCGCATGCGACCAAGGATTCCTTGATTCTCTTTGATGAATTGGGACGCGGAACTGCAACTTATGACGGAATGG
CTCTGGCCCAATCCATCATCGAATACATCCATGAACATATCGGAGCCAAAACCCTCTTTGCGACCCACTACCATGAGTTG
ACCAGTCTGGAGTCTAGCTTGGAACACTTGGTCAATGTCCACGTGGCAACCTTAGAACAGGATGGACAGGTTACCTTCCT
TCACAAGATTGAACCAGGTCCAGCTGATAAATCCTACGGTATCCATGTGGCCAAGATTGCTGGCTTACCAGCAGAACTTT
TAGCAAGAGCGGATAAGATTTTAACGCAACTGGAGAGTCAAGGGGGAGAAAGTCCTGCTCCGATGAGCCAAACAAGTGCT
GTCACAGAACAGATGTCACTCTTTGATGCGCCTGAAGAACATCCTATCCTAGCAGAATTAGCTAAACTGGATGTGTACAA
TATGACACCTATGCAGGCTATGAATGTCTTGGTCGAGCTCAAACAAAAGTTATAA

Domains

Predicted by InterProScan.

MutS domain I (MutS_I)

(8-118)

MutS domain V (MutS_V)

(599-785)

MutS domain II (MutS_II)

(126-239)

MutS family domain IV (MutS_IV)

(415-505)

MutS domain III (MutS_III)

(256-546)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

95.853

100

0.959
  mutS Pseudomonas stutzeri strain ATCC 17587

37.002

100

0.374