Detailed information NTG0337221

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EQH37_RS08805
• Genome accession: NZ_CP035243
• Coordinates: 1775006..1776073 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain TVO_1901946
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1770006..1781073

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH37_RS08780 (EQH37_09305)	treR	1770193..1770903 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
EQH37_RS08785 (EQH37_09310)	-	1770936..1771739 (-)	804	WP_000157656.1	ABC transporter ATP-binding protein	-
EQH37_RS08790 (EQH37_09315)	-	1771752..1772629 (-)	878	Protein_1767	ABC transporter permease	-
EQH37_RS08795 (EQH37_09320)	-	1772641..1773450 (-)	810	Protein_1768	ABC transporter substrate-binding protein	-
EQH37_RS08800 (EQH37_09325)	amiF	1774069..1774995 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
EQH37_RS08805 (EQH37_09330)	amiE	1775006..1776073 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
EQH37_RS08810 (EQH37_09335)	amiD	1776082..1777008 (-)	927	WP_054407486.1	oligopeptide ABC transporter permease OppC	Regulator
EQH37_RS08815 (EQH37_09340)	amiC	1777008..1778504 (-)	1497	WP_054407484.1	ABC transporter permease	Regulator
EQH37_RS08820 (EQH37_09345)	amiA3	1778571..1780550 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=337221 EQH37_RS08805 WP_000159554.1 1775006..1776073(-) (amiE) [Streptococcus pneumoniae strain TVO_1901946]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=337221 EQH37_RS08805 WP_000159554.1 1775006..1776073(-) (amiE) [Streptococcus pneumoniae strain TVO_1901946]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGCATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541