Detailed information NTG0337119

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH38_RS02465
• Genome accession: NZ_CP035242
• Coordinates: 441086..442096 (+)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901947
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 436086..447096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH38_RS02435 (EQH38_02555)	-	436956..437162 (+)	207	WP_000503437.1	hypothetical protein	-
EQH38_RS02440 (EQH38_02560)	-	437159..437353 (+)	195	WP_000820182.1	hypothetical protein	-
EQH38_RS02445 (EQH38_02565)	-	437340..438224 (+)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
EQH38_RS02450 (EQH38_02570)	-	438226..438963 (+)	738	WP_000832843.1	ABC transporter permease	-
EQH38_RS02455 (EQH38_02575)	-	438963..440060 (+)	1098	WP_050148143.1	sensor histidine kinase	-
EQH38_RS02460 (EQH38_02580)	-	440062..440661 (+)	600	WP_000866724.1	response regulator transcription factor	-
EQH38_RS02465 (EQH38_02585)	ccpA	441086..442096 (+)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH38_RS02470 (EQH38_02590)	-	442392..443354 (-)	963	WP_001124771.1	asparaginase	-
EQH38_RS02475 (EQH38_02595)	-	443420..444808 (+)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
EQH38_RS02480 (EQH38_02600)	-	444843..445295 (-)	453	WP_000079148.1	universal stress protein	-
EQH38_RS02485 (EQH38_02605)	-	445366..445648 (+)	283	Protein_475	hypothetical protein	-
EQH38_RS02490 (EQH38_02610)	-	445804..447018 (+)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=337119 EQH38_RS02465 WP_000990607.1 441086..442096(+) (ccpA) [Streptococcus pneumoniae strain TVO_1901947]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=337119 EQH38_RS02465 WP_000990607.1 441086..442096(+) (ccpA) [Streptococcus pneumoniae strain TVO_1901947]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCCAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568