Detailed information NTG0336998

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH41_RS09490
• Genome accession: NZ_CP035239
• Coordinates: 1895114..1896124 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_TIGR4
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1890114..1901124

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH41_RS09465 (EQH41_10090)	-	1891099..1891393 (-)	295	Protein_1883	hypothetical protein	-
EQH41_RS09470 (EQH41_10095)	-	1891555..1892007 (+)	453	WP_000079148.1	universal stress protein	-
EQH41_RS09475 (EQH41_10100)	-	1892042..1893430 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
EQH41_RS09480 (EQH41_10105)	-	1893496..1894458 (+)	963	WP_001124777.1	asparaginase	-
EQH41_RS09485 (EQH41_10110)	-	1894487..1895050 (-)	564	WP_001092024.1	hypothetical protein	-
EQH41_RS09490 (EQH41_10115)	ccpA	1895114..1896124 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH41_RS09495 (EQH41_10120)	-	1896549..1897148 (-)	600	WP_000866703.1	response regulator transcription factor	-
EQH41_RS09500 (EQH41_10125)	-	1897149..1898246 (-)	1098	WP_000893503.1	sensor histidine kinase	-
EQH41_RS09505 (EQH41_10130)	-	1898246..1898983 (-)	738	WP_000832915.1	ABC transporter permease	-
EQH41_RS09510 (EQH41_10135)	-	1898985..1899869 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
EQH41_RS09515 (EQH41_10140)	-	1899856..1900050 (-)	195	WP_000820189.1	hypothetical protein	-
EQH41_RS09520	-	1900047..1900253 (-)	207	Protein_1894	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=336998 EQH41_RS09490 WP_000990607.1 1895114..1896124(-) (ccpA) [Streptococcus pneumoniae strain TVO_TIGR4]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=336998 EQH41_RS09490 WP_000990607.1 1895114..1896124(-) (ccpA) [Streptococcus pneumoniae strain TVO_TIGR4]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568