Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FZN31_RS03950 Genome accession   NZ_CP043414
Coordinates   824616..825275 (-) Length   219 a.a.
NCBI ID   WP_001221493.1    Uniprot ID   Q3YXL4
Organism   Escherichia coli strain EC42405     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 819616..830275
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FZN31_RS03920 (FZN31_04030) - 819772..820719 (+) 948 WP_001298369.1 iron-siderophore ABC transporter substrate-binding protein -
  FZN31_RS03925 (FZN31_04035) - 820716..821604 (+) 889 Protein_773 MurR/RpiR family transcriptional regulator -
  FZN31_RS03930 (FZN31_04040) ygiN 821649..821963 (-) 315 WP_000633737.1 putative quinol monooxygenase -
  FZN31_RS03935 (FZN31_04045) mdaB 821994..822575 (-) 582 WP_105276764.1 NADPH:quinone oxidoreductase MdaB -
  FZN31_RS03940 (FZN31_04050) ygiZ 822892..823224 (+) 333 WP_105276763.1 DUF2645 family protein -
  FZN31_RS03945 (FZN31_04055) qseC 823270..824619 (-) 1350 WP_000673371.1 quorum sensing histidine kinase QseC -
  FZN31_RS03950 (FZN31_04060) ciaR 824616..825275 (-) 660 WP_001221493.1 quorum sensing response regulator transcription factor QseB Regulator
  FZN31_RS03955 (FZN31_04065) ygiW 825427..825819 (+) 393 WP_105276760.1 OB fold stress tolerance protein YgiW -
  FZN31_RS03960 (FZN31_04070) ygiV 825872..826354 (+) 483 WP_000793821.1 GyrI-like domain-containing protein -
  FZN31_RS03965 (FZN31_04075) ygiS 826463..828070 (+) 1608 WP_105287692.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24687.63 Da        Isoelectric Point: 6.9850

>NTDB_id=336995 FZN31_RS03950 WP_001221493.1 824616..825275(-) (ciaR) [Escherichia coli strain EC42405]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=336995 FZN31_RS03950 WP_001221493.1 824616..825275(-) (ciaR) [Escherichia coli strain EC42405]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTATTAATCCTGACTGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTACATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3YXL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment