Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FZN31_RS00180 Genome accession   NZ_CP043414
Coordinates   36867..37457 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain EC42405     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 31867..42457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FZN31_RS00165 (FZN31_00165) ilvN 33146..33436 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  FZN31_RS00170 (FZN31_00170) - 33698..34963 (+) 1266 WP_105288208.1 hypothetical protein -
  FZN31_RS00175 (FZN31_00175) - 35177..36706 (+) 1530 WP_032185538.1 hypothetical protein -
  FZN31_RS00180 (FZN31_00180) letA 36867..37457 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FZN31_RS00185 (FZN31_00185) uhpB 37457..38959 (+) 1503 WP_105288209.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FZN31_RS00190 (FZN31_00190) uhpC 38969..40288 (+) 1320 WP_088541982.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FZN31_RS00195 (FZN31_00195) uhpT 40426..41817 (+) 1392 WP_000879199.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=336980 FZN31_RS00180 WP_000633668.1 36867..37457(+) (letA) [Escherichia coli strain EC42405]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=336980 FZN31_RS00180 WP_000633668.1 36867..37457(+) (letA) [Escherichia coli strain EC42405]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCACTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATTATGCTCTCCGTT
CATGACAGTCCGGCACTGGTTGAGCAGGCGCTTAACGCGGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTGATTGCAGCGGTGCATACGGTTGCTACGGGGGGATGTTATTTGACACCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTGACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAACCTGATGGAAAAACTGGGCGTCAGTAACGACGTGGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378