Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FZN32_RS18115 Genome accession   NZ_CP043406
Coordinates   3759177..3759809 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain NMBU-W13E19     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3754177..3764809
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FZN32_RS18090 (FZN32_18570) yhfG 3754309..3754476 (+) 168 WP_000736851.1 YhfG family protein -
  FZN32_RS18095 (FZN32_18575) fic 3754466..3755068 (+) 603 WP_001280634.1 putative adenosine monophosphate-protein transferase Fic -
  FZN32_RS18100 (FZN32_18580) pabA 3755100..3755663 (+) 564 WP_000601862.1 aminodeoxychorismate synthase component 2 -
  FZN32_RS18105 (FZN32_18585) argD 3755749..3756969 (+) 1221 WP_000190012.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  FZN32_RS18110 (FZN32_18590) yhfK 3757036..3759126 (-) 2091 WP_001309799.1 YccS/YhfK family putative transporter -
  FZN32_RS18115 (FZN32_18595) crp 3759177..3759809 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  FZN32_RS18120 (FZN32_18600) yhfA 3760111..3760515 (+) 405 WP_001148908.1 OsmC family protein -
  FZN32_RS18125 (FZN32_18605) prkB 3760570..3761439 (-) 870 WP_001274680.1 phosphoribulokinase -
  FZN32_RS18130 (FZN32_18610) yheU 3761493..3761711 (-) 219 WP_000907085.1 YheU family protein -
  FZN32_RS18135 (FZN32_18615) yheT 3761705..3762727 (-) 1023 WP_000057395.1 hydrolase -
  FZN32_RS18140 (FZN32_18620) yheS 3762727..3764640 (-) 1914 WP_000634840.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=336956 FZN32_RS18115 WP_000242755.1 3759177..3759809(-) (crp) [Escherichia coli strain NMBU-W13E19]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=336956 FZN32_RS18115 WP_000242755.1 3759177..3759809(-) (crp) [Escherichia coli strain NMBU-W13E19]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAGGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACTGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment