Detailed information NTG0336815

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FY406_RS02345
• Genome accession: NZ_CP043405
• Coordinates: 501130..503679 (-)
• Length: 849 a.a.
• NCBI ID: WP_003089919.1
• Uniprot ID: A0ABN0GW52
• Organism: Streptococcus ratti strain ATCC 31377
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 496130..508679

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FY406_RS02330 (FY406_02330)	-	497625..498185 (-)	561	WP_003089912.1	DNA-3-methyladenine glycosylase I	-
FY406_RS02335 (FY406_02335)	ruvA	498223..498816 (-)	594	WP_003089915.1	Holliday junction branch migration protein RuvA	Machinery gene
FY406_RS02340 (FY406_02340)	hexB	499101..501056 (-)	1956	WP_003089917.1	DNA mismatch repair endonuclease MutL	Machinery gene
FY406_RS02345 (FY406_02345)	hexA	501130..503679 (-)	2550	WP_003089919.1	DNA mismatch repair protein MutS	Machinery gene
FY406_RS02350 (FY406_02350)	-	503672..504019 (-)	348	WP_003089922.1	YlbF family regulator	-
FY406_RS02355 (FY406_02355)	argR	504016..504453 (-)	438	WP_003089924.1	arginine repressor	-
FY406_RS02360 (FY406_02360)	-	504686..505804 (-)	1119	WP_003089932.1	aminotransferase	-
FY406_RS02365 (FY406_02365)	arcD	506068..507477 (-)	1410	WP_003089933.1	arginine-ornithine antiporter	-
FY406_RS02370 (FY406_02370)	arcC	507495..508448 (-)	954	WP_003089935.1	carbamate kinase	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 95372.86 Da
• Isoelectric Point: 4.8366

>NTDB_id=336815 FY406_RS02345 WP_003089919.1 501130..503679(-) (hexA) [Streptococcus ratti strain ATCC 31377]
MTKEKLSPGMKQYLDIKEDYPDAFLLFRMGDFYELFYEDAVKAARILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKTAVGVVKREVVQVITPGTLVDSAKPDSANNFLVALDTDGSRFGLSYMDLSTGEFYATTLADLTA
VRSEVLNLKARELVLGFDLDEEAENIFRKQMNLLLSVEKTVYEDLHLLDSQLTDLELAAAGKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMTYTTKSSLDLLENARSGKKHGSLYWLLDETKTAMGTRLLRTWIDRPLVSHKLISKRQDIIQVFLDQFF
ERSDLSDSLKGVYDIERLASRVSFGKANPKDLLQLGQTLAQVPIIKAILESFDSPALEDLVGQIDPLPELEELIRSAIDP
NAPMTITEGSIIRAGFDETLDKYRKVMREGTGWIADIEAKERTASGISTLKIDYNKKDGYYFHVTNSNLSLVPEYFFRKA
TLKNSERFGTAELAKIEGEMLEAREESANLEYDIFMRIRAQVETYIERLQTLAKYLATVDVLQSLAVVAENNHYVRPVFN
DDKIISIENGRHAVIEKVMGSQEYIPNTIHFDQKTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADSAALPVFDA
IFTRIGAADDLISGQSTFMVEMMEANHAIKAADENSLILFDELGRGTATYDGMALAQAIIEYVHDKIKAKTMFATHYHEL
TDLSTTLTDLVNVHVATLEKNGEVTFLHKITDGPADKSYGIHVAKIAGLPRDLLNRADHILADLEKTSAAVSVNLKNDKT
PEQPAQEQLSLFNINDDYKDLLERLRQLDVASLTPREAMNALFDLKDML

Nucleotide

• Length: 2550 bp

>NTDB_id=336815 FY406_RS02345 WP_003089919.1 501130..503679(-) (hexA) [Streptococcus ratti strain ATCC 31377]
ATGACTAAGGAAAAGCTCTCTCCGGGAATGAAGCAGTATTTGGATATCAAAGAAGATTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGATTTTTACGAACTTTTTTACGAAGATGCTGTCAAGGCTGCCAGAATTTTAGAAATCAGCCTAACCAGCC
GCAACAAAAATGCAGACAATCCCATCCCTATGGCGGGGGTTCCCTATCATTCAGCTCAGCAGTATATTGATGTTTTAGTT
GAGCTTGGTTATAAGGTTGCTATTGCTGAACAGATGGAGGATCCGAAGACAGCGGTCGGTGTTGTTAAGCGTGAAGTTGT
TCAGGTCATCACACCAGGGACACTGGTGGATTCGGCTAAACCGGACAGTGCCAATAATTTCTTAGTTGCTCTTGATACAG
ATGGCAGTCGTTTTGGTCTGTCTTATATGGACTTATCAACTGGGGAATTTTATGCGACGACCTTAGCAGATTTAACAGCA
GTCAGAAGTGAGGTGCTTAATCTTAAGGCGCGTGAGCTGGTTCTTGGTTTTGACCTTGATGAAGAAGCAGAAAATATTTT
CCGCAAGCAGATGAATCTTCTGCTGTCTGTTGAAAAAACGGTTTATGAGGATCTTCATCTGCTGGACAGCCAGCTGACTG
ATTTGGAGCTTGCCGCAGCCGGTAAGCTTTTGCAGTATGTACACACAACCCAAAAACGAGAACTGAGTCATTTACAAAAG
CTTGTACACTATGAAATTAAAGACTATTTGCAAATGACCTACACCACCAAATCCAGCTTGGACTTGTTAGAAAATGCTCG
CAGCGGGAAAAAACACGGCAGTCTCTATTGGCTTTTAGATGAGACAAAAACAGCCATGGGAACGCGGCTTTTACGGACTT
GGATTGATCGTCCTTTGGTTAGCCACAAGCTTATCAGCAAACGTCAGGATATTATTCAGGTTTTTTTGGATCAGTTTTTT
GAGCGCAGTGATTTGAGTGACAGTTTAAAAGGAGTTTATGATATTGAGCGTTTGGCCAGCCGAGTCTCTTTTGGCAAAGC
CAATCCTAAAGACCTCTTGCAGCTAGGTCAGACCTTGGCTCAGGTTCCAATCATTAAAGCTATTTTGGAAAGTTTTGACA
GTCCTGCTTTGGAGGATTTAGTCGGTCAAATCGATCCCCTGCCAGAGTTAGAAGAGCTGATTCGCTCAGCCATTGATCCT
AACGCACCAATGACGATTACAGAAGGTAGTATTATTCGTGCAGGTTTTGATGAGACCTTGGATAAATACCGCAAAGTTAT
GCGTGAGGGAACGGGCTGGATTGCTGATATTGAGGCTAAAGAACGAACAGCCAGCGGTATTTCCACCTTGAAGATTGATT
ACAACAAAAAAGACGGCTACTATTTCCATGTCACAAATTCCAATCTTTCTTTGGTACCTGAGTATTTCTTCAGAAAGGCA
ACCCTGAAAAATTCTGAGCGCTTTGGTACAGCAGAGCTGGCCAAAATTGAAGGTGAGATGCTGGAAGCGCGAGAGGAATC
AGCTAATTTAGAGTATGATATTTTCATGCGGATTAGAGCACAGGTCGAAACTTATATTGAGCGTCTGCAAACTCTGGCTA
AATACTTAGCAACTGTTGATGTTTTGCAAAGTCTCGCAGTGGTTGCTGAAAACAACCACTATGTCCGGCCAGTTTTTAAT
GATGATAAGATTATCAGCATTGAAAATGGTCGTCATGCGGTGATTGAAAAAGTCATGGGCTCTCAAGAGTATATTCCTAA
TACGATTCATTTTGATCAAAAGACCAGTATCCAGCTGATTACGGGCCCTAATATGAGCGGAAAGTCCACCTACATGCGTC
AGCTTGCTCTGACTGTGATCATGGCGCAAATGGGCTCTTTTGTTGCAGCAGATTCGGCTGCTCTGCCTGTTTTTGACGCT
ATTTTCACCCGTATCGGTGCAGCAGATGATTTGATTTCCGGCCAGTCCACCTTTATGGTCGAAATGATGGAAGCTAATCA
TGCAATCAAAGCTGCTGATGAAAACTCTCTGATTCTCTTTGATGAACTGGGACGCGGGACAGCTACCTATGACGGGATGG
CTCTGGCACAGGCAATTATTGAATATGTTCATGATAAAATTAAGGCTAAAACCATGTTTGCTACTCATTATCATGAATTG
ACAGACCTGTCAACTACATTGACAGACCTTGTCAATGTCCATGTTGCGACTCTGGAAAAAAATGGAGAGGTGACTTTCCT
GCACAAAATTACAGATGGTCCGGCAGATAAATCTTATGGGATTCATGTAGCAAAAATTGCCGGTCTGCCTAGAGATTTAT
TAAACCGTGCCGATCATATTTTGGCAGACTTGGAAAAGACCAGCGCTGCCGTTTCGGTTAATCTAAAAAATGATAAAACC
CCTGAACAGCCTGCCCAAGAACAGCTGTCGCTCTTCAATATCAATGATGATTATAAGGATTTGTTGGAAAGATTAAGACA
GCTGGATGTTGCCAGCCTAACCCCAAGAGAGGCCATGAATGCTCTCTTTGATTTAAAAGATATGCTATAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.614	100	0.716
mutS	Pseudomonas stutzeri strain ATCC 17587	37.822	100	0.38