Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FY406_RS02340 Genome accession   NZ_CP043405
Coordinates   499101..501056 (-) Length   651 a.a.
NCBI ID   WP_003089917.1    Uniprot ID   A0ABN0GWD5
Organism   Streptococcus ratti strain ATCC 31377     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 494101..506056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS02315 (FY406_02315) spx 494415..494813 (-) 399 WP_003089907.1 transcriptional regulator Spx -
  FY406_RS02320 (FY406_02320) recA 494898..496046 (-) 1149 WP_003089908.1 recombinase RecA Machinery gene
  FY406_RS02325 (FY406_02325) cinA 496089..497345 (-) 1257 WP_003089911.1 competence/damage-inducible protein A Machinery gene
  FY406_RS02330 (FY406_02330) - 497625..498185 (-) 561 WP_003089912.1 DNA-3-methyladenine glycosylase I -
  FY406_RS02335 (FY406_02335) ruvA 498223..498816 (-) 594 WP_003089915.1 Holliday junction branch migration protein RuvA Machinery gene
  FY406_RS02340 (FY406_02340) hexB 499101..501056 (-) 1956 WP_003089917.1 DNA mismatch repair endonuclease MutL Machinery gene
  FY406_RS02345 (FY406_02345) hexA 501130..503679 (-) 2550 WP_003089919.1 DNA mismatch repair protein MutS Machinery gene
  FY406_RS02350 (FY406_02350) - 503672..504019 (-) 348 WP_003089922.1 YlbF family regulator -
  FY406_RS02355 (FY406_02355) argR 504016..504453 (-) 438 WP_003089924.1 arginine repressor -
  FY406_RS02360 (FY406_02360) - 504686..505804 (-) 1119 WP_003089932.1 aminotransferase -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 73470.83 Da        Isoelectric Point: 6.0665

>NTDB_id=336814 FY406_RS02340 WP_003089917.1 499101..501056(-) (hexB) [Streptococcus ratti strain ATCC 31377]
MSKIIELPEILANQIAAGEVIERPASVVKELVENAIDAASSQITVDIEESGLKKIQVTDNGQGMEQADAAMSLHRHATSK
IKSQADLFRIRTLGFRGEALPSIASVSRLSIKTASDRESYGTFLLANGGKVEKEEAVSTPVGTKITVEDLFFNTPARLKY
MKSLQAELAHIIDVLNRLSLAHPEIAFTLINDGRELIRTSGNGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAIIDIQIDPYLADVNVHPTKQEVRISKEKELMQLISL
AIAESLRKQDLIPDALENLAKSSTYHNHKAEQTSLPLKQSTIYYDKDKNDFFLKEATVAEKSAKFTQVDSSVKESVDSPS
ASAVKYAERRAYSQDGKDHPDIVLKDKNQKRQLSKLVKDLENEEVSSFPELDYFGQMHGTYLFAQGEGGLYIIDQHAAQE
RVKYEYYREKIGQVDSSLQQLLVPYLFEFPANDFVTLQEKMPILNEIGIYLEAYGENTFILREHPIWLQEKEIESAIYEM
CDMLLLTNEVSIKNYRAELAVMMSCKRSIKANHTLDDYSARNLLSQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQE
NHTSLRELGKY

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=336814 FY406_RS02340 WP_003089917.1 499101..501056(-) (hexB) [Streptococcus ratti strain ATCC 31377]
ATGTCAAAAATTATTGAATTGCCAGAAATATTAGCCAATCAGATTGCTGCCGGTGAAGTCATTGAAAGACCGGCCAGTGT
CGTTAAAGAATTAGTTGAAAATGCCATTGACGCTGCCAGCAGTCAGATTACGGTAGACATTGAAGAATCGGGTCTTAAAA
AAATTCAGGTGACAGACAACGGTCAGGGAATGGAGCAGGCTGATGCAGCGATGAGTTTGCACCGCCATGCTACTAGTAAA
ATCAAAAGTCAGGCTGATCTTTTTAGGATTCGTACGCTTGGTTTTCGCGGAGAAGCTCTGCCTTCCATTGCTTCAGTCAG
CCGTTTAAGTATAAAAACTGCTAGTGATAGAGAGAGCTATGGAACCTTTCTTTTGGCTAACGGGGGCAAGGTTGAAAAAG
AAGAGGCCGTCAGTACGCCAGTCGGAACAAAAATAACGGTTGAGGATTTGTTTTTCAACACCCCGGCTAGGTTAAAGTAT
ATGAAAAGTCTGCAGGCTGAGCTAGCTCATATTATTGATGTGCTTAACCGTCTCAGTCTGGCTCATCCTGAGATTGCTTT
TACTCTAATTAATGACGGCCGTGAGTTAATAAGAACTTCAGGCAACGGTGATTTACGCCAAGCTATTGCGGGTATTTACG
GCCTTAATACGGCTAAAAAGATGATTGAAATTTCCAATGCTGACCTTGATTTTGAGGTATCCGGCTATATCAGCCTGCCT
GAGCTGACAAGGGCAAACCGTAATTATATCACCATTCTCATCAATGGGCGCTATATTAAGAATTTTCTGCTGAACCGGGC
AATTTTAGACGGTTACGGCTCTAAGCTGATGGTGGGGCGTTTTCCGATTGCGATTATCGATATTCAGATTGATCCTTATT
TGGCGGATGTCAATGTCCATCCTACCAAGCAGGAAGTCCGCATTTCTAAGGAAAAGGAGCTGATGCAGCTTATCAGCTTA
GCTATTGCTGAGAGCCTCAGGAAACAAGACTTAATTCCTGATGCCCTGGAAAATTTGGCTAAATCCAGCACCTACCATAA
TCATAAAGCGGAGCAAACTTCTTTGCCTTTGAAGCAGTCCACTATCTATTATGATAAGGATAAGAATGATTTTTTCCTTA
AGGAAGCGACTGTCGCAGAAAAATCAGCGAAGTTTACACAAGTTGACAGTTCTGTAAAGGAGTCTGTTGACAGTCCATCA
GCCAGTGCAGTCAAATATGCTGAGCGCAGGGCCTACAGCCAAGATGGTAAAGACCACCCTGATATTGTCTTAAAAGATAA
AAATCAGAAGCGACAGCTCAGCAAACTTGTCAAAGATTTGGAAAATGAAGAAGTTTCATCTTTCCCAGAGCTAGATTATT
TTGGTCAGATGCATGGAACCTATCTCTTTGCTCAAGGAGAAGGCGGTCTTTATATTATTGATCAGCACGCTGCACAGGAA
CGTGTAAAGTATGAGTATTACCGTGAAAAAATCGGTCAGGTTGACAGCAGTTTACAGCAGCTTTTGGTGCCTTATTTGTT
TGAGTTTCCAGCTAATGACTTTGTGACTCTGCAGGAAAAGATGCCAATTCTCAATGAAATCGGCATCTATCTGGAAGCCT
ATGGAGAAAATACTTTCATTTTAAGAGAGCACCCTATCTGGCTGCAGGAAAAAGAAATCGAATCTGCTATTTATGAAATG
TGTGACATGCTGCTTTTGACAAATGAAGTGTCCATAAAAAATTATCGGGCAGAGCTGGCTGTTATGATGTCCTGCAAGCG
CAGTATCAAAGCTAATCATACCTTAGACGACTATTCTGCTAGGAACCTTTTGAGCCAGCTGTCACAGTGTAAAAATCCTT
ACAACTGTCCGCACGGCCGGCCGGTTTTAGTCAATTTCACCAAGTCTGACATGGAAAAGATGTTTCGCCGGATTCAGGAA
AACCATACTAGTTTGCGAGAGCTGGGAAAATACTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(453-595)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.732

100

0.713

Multiple sequence alignment