Detailed information NTG0336647

Bioinformatically predicted

Overview

• Name: amiA3
• Type: Regulator
• Locus tag: EQH45_RS01965
• Genome accession: NZ_CP035235
• Coordinates: 377952..379934 (+)
• Length: 660 a.a.
• NCBI ID: WP_000842784.1
• Uniprot ID: A0A6I3TKG5
• Organism: Streptococcus pneumoniae strain TVO_1902276
• Function: binding to XIP (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	374729..377642	377952..379934	flank	310

Gene organization within MGE regions

Location: 374729..379934

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH45_RS01955 (EQH45_02075)	-	374729..375985 (-)	1257	WP_000436461.1	ISL3-like element IS1167A family transposase	-
EQH45_RS01960 (EQH45_02080)	-	376296..377642 (-)	1347	WP_001808790.1	IS1380-like element ISSpn5 family transposase	-
EQH45_RS01965 (EQH45_02085)	amiA3	377952..379934 (+)	1983	WP_000842784.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 660 a.a.
• Molecular weight: 73124.73 Da
• Isoelectric Point: 4.7570

>NTDB_id=336647 EQH45_RS01965 WP_000842784.1 377952..379934(+) (amiA3) [Streptococcus pneumoniae strain TVO_1902276]
MKSSRLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDPDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPS
MAEDWSVSKDGLTYTYTIRKDAKWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPYLLKSIVTKSSVEFAKNPNYWD
KDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARLYPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSK
TSEEQKTSTKKALLNKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVTYGDEWKDV
NLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQRVQSMKQSLEATLGADNVVIDIQQLQKDEV
NNITYFAENAAGEDWDLSDNVGWGPDFADPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETT
DVAKRYDKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQDKAVTVDEYQKAQEKW
MKEKEESNKKAQEDLAKHVK

Nucleotide

• Length: 1983 bp

>NTDB_id=336647 EQH45_RS01965 WP_000842784.1 377952..379934(+) (amiA3) [Streptococcus pneumoniae strain TVO_1902276]
ATGAAAAGTTCAAGACTATTTGCCCTTGCGGGCGTGACATTATTGGCGGCGACTACTTTAGCTGCATGCTCTGGATCAGG
TTCAAGCACTAAAGGTGAGAAGACATTCTCATACATTTATGAGACAGACCCTGATAACCTCAACTATTTGACAACTGCTA
AGGCTGCGACAGCAAATATTACCAGTAACGTGGTTGATGGTTTGCTAGAAAATGATCGCTACGGGAACTTTGTGCCGTCT
ATGGCTGAGGATTGGTCTGTATCCAAGGATGGATTGACTTACACTTATACTATCCGTAAGGATGCAAAATGGTATACTTC
TGAAGGTGAAGAATACGCGGCAGTCAAAGCTCAAGACTTTGTAACAGGACTAAAATATGCTGCTGATAAAAAATCAGATG
CTCTTTACCTTGTTCAAGAATCAATCAAAGGGTTGGATGCCTATGTAAAAGGGGAAATCAAAGATTTCTCACAAGTAGGA
ATTAAGGCTCTGGATGAACAGACAGTTCAGTACACTTTGAACAAACCAGAAAGCTTCTGGAATTCTAAGACAACCATGGG
TGTGCTTGCGCCAGTTAATGAAGAGTTTTTGAATTCAAAAGGGGATGATTTTGCCAAAGCTACGGATCCAAGTAGTCTCT
TGTATAACGGTCCTTATTTGTTGAAATCCATTGTGACCAAATCTTCTGTTGAATTTGCGAAAAATCCGAACTACTGGGAT
AAGGACAATGTGCATATTGACAAAGTTAAATTGTCATTCTGGGATGGTCAAGATACCAGCAAACCTGCAGAAAACTTTAA
AGATGGTAGCCTTACAGCAGCTCGTCTCTATCCAACAAGTGCAAGTTTCGCAGAGCTTGAGAAGAGTATGAAGGACAATA
TTGTCTATACTCAACAAGACTCTATTACGTATCTAGTTGGTACAAATATTGACCGTCAGTCCTATAAATATACATCTAAG
ACCAGTGAAGAACAAAAAACATCTACGAAAAAGGCTCTCTTAAACAAGGATTTCCGTCAGGCTATTGCATTTGGATTTGA
CCGTACAGCCTATGCCTCTCAGTTGAATGGACAAACTGGAGCAAGCAAAATCTTACGTAATATCTTTGTTCCACCAACAT
TTGTTCAAGCAGATGGTAAAAACTTTGGCGATATGGTCAAAGAGAAATTGGTCACTTATGGGGATGAATGGAAGGATGTT
AATCTTGCAGATTCTCAGGATGGTCTTTACAATCCAGAAAAAGCCAAGGCTGAATTTGCTAAAGCTAAATCAGCTTTACA
AGCAGAAGGTGTGACTTTCCCAATTCATTTGGATATGCCAGTTGACCAGACAGCAACTACAAAAGTTCAGCGCGTCCAAT
CTATGAAACAATCCTTGGAAGCAACTTTAGGAGCGGATAATGTAGTCATTGATATTCAACAACTACAAAAAGACGAAGTA
AACAATATTACATATTTTGCTGAAAATGCTGCTGGTGAAGACTGGGATTTATCAGATAATGTCGGTTGGGGTCCAGACTT
TGCCGATCCATCAACCTACCTTGATATCATCAAACCATCTGTAGGAGAAAGTACTAAAACATATTTAGGGTTTGACTCAG
GGGAAGATAATGTAGCTGCTAAAAAAGTAGGTCTATATGACTACGAAAAATTGGTTACTGAGGCTGGTGATGAGACTACA
GATGTTGCTAAACGCTATGATAAATACGCTGCAGCCCAAGCTTGGTTGACAGATAGTGCTTTGATTATTCCAACTACATC
TCGTACAGGGCGTCCAATCTTGTCTAAGATGGTACCATTTACAATACCATTTGCATTGTCAGGAAATAAAGGCACAAGTG
AACCAGTCTTGTATAAATACTTGGAACTTCAAGACAAGGCAGTCACTGTAGATGAATACCAAAAAGCTCAGGAAAAATGG
ATGAAAGAAAAAGAAGAGTCTAATAAAAAGGCTCAAGAAGATCTCGCAAAACATGTGAAATAA

Domains

Predicted by InterproScan.

• Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5) (77-519)

3D structure

• AlphaFold DB: A0A6I3TKG5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiA3	Streptococcus thermophilus LMD-9	58.245	100	0.583
amiA3	Streptococcus thermophilus LMG 18311	57.943	100	0.58
amiA	Streptococcus salivarius strain HSISS4	57.943	100	0.58