Detailed information NTG0033664

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SGGBAA2069_RS11165
• Genome accession: NC_015215
• Coordinates: 2251287..2253857 (-)
• Length: 856 a.a.
• NCBI ID: WP_009855174.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2246287..2258857

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGGBAA2069_RS12215	-	2246377..2246550 (-)	174	WP_009855168.1	hypothetical protein	-
SGGBAA2069_RS11140 (SGGBAA2069_c21920)	-	2246600..2247064 (-)	465	WP_009855169.1	hypothetical protein	-
SGGBAA2069_RS11145 (SGGBAA2069_c21930)	-	2247134..2247541 (-)	408	WP_009855170.1	hypothetical protein	-
SGGBAA2069_RS11150 (SGGBAA2069_c21940)	-	2247704..2248558 (+)	855	WP_009855171.1	helix-turn-helix domain-containing protein	-
SGGBAA2069_RS11155 (SGGBAA2069_c21950)	ruvA	2248632..2249225 (-)	594	WP_009855172.1	Holliday junction branch migration protein RuvA	Machinery gene
SGGBAA2069_RS11160 (SGGBAA2069_c21960)	hexB	2249227..2251170 (-)	1944	WP_012962624.1	DNA mismatch repair endonuclease MutL	Machinery gene
SGGBAA2069_RS11165 (SGGBAA2069_c21970)	hexA	2251287..2253857 (-)	2571	WP_009855174.1	DNA mismatch repair protein MutS	Machinery gene
SGGBAA2069_RS11170 (SGGBAA2069_c21980)	-	2253844..2254200 (-)	357	WP_009855175.1	YlbF family regulator	-
SGGBAA2069_RS11175 (SGGBAA2069_c21990)	argR	2254197..2254634 (-)	438	WP_003066930.1	arginine repressor	-
SGGBAA2069_RS11180 (SGGBAA2069_c22000)	argS	2254824..2256515 (+)	1692	WP_009855176.1	arginine--tRNA ligase	-
SGGBAA2069_RS11185 (SGGBAA2069_c22010)	-	2256628..2256921 (+)	294	WP_009855177.1	bacteriocin immunity protein	-
SGGBAA2069_RS11190 (SGGBAA2069_c22020)	-	2256962..2258467 (-)	1506	WP_013643548.1	prolyl oligopeptidase family serine peptidase	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95896.23 Da
• Isoelectric Point: 4.8516

>NTDB_id=33664 SGGBAA2069_RS11165 WP_009855174.1 2251287..2253857(-) (hexA) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MTKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKTFGLAYMDVSTGEFFSTSLSDFTS
LRSEILNLKAREVVVGYELSETEQHSLVKQLNLLLSFEQERYEDVHLIDPDLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQAQIEERQNIVQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLAQVPTIKAILESFESPHLDKLVNNIDTLPELESLIRSAIAP
DAPAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRGQVERYITRLQDLAKAISTVDVLQSLAVVAENNHYVRPTFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFDADINIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVNLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASSQSLILFDELGRGTATYDGMALAQSIIEYIHNHIGAKTMFATHYHEL
TALSTSLTHLINVHVATLEKNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEELLQRADSILTNLESGAAQLQLTPEVEVG
PITVKSEVAEPVAEQLSLFADDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2571 bp

>NTDB_id=33664 SGGBAA2069_RS11165 WP_009855174.1 2251287..2253857(-) (hexA) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGACAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGACGTAAAAAAAGATTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTATGAATTATTTTATGATGATGCGGTTAAAGCTGCACAGATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAATCCAATTCCAATGGCAGGTGTGCCTTATCATTCTGCGCAACAATACATTGATGTATTAGTG
GAAATGGGTTACAAGGTGGCAATTGCTGAGCAAATGGAAGACCCAAAACAAGCCGTCGGTGTGGTTAAACGTGAAGTCGT
TCAAGTGATTACGCCAGGAACAGCTGTCGATTCCTCTAAACCAGATAATGCTAACAATTTCTTGGTGGCTATCGATTCTG
ACGGCAAAACGTTTGGGCTAGCCTATATGGACGTGTCAACAGGTGAATTTTTCTCAACAAGTCTTTCTGATTTTACAAGC
CTTAGAAGTGAAATTCTGAACCTTAAAGCGCGTGAAGTTGTTGTTGGTTATGAGCTTTCTGAAACAGAGCAACATAGCTT
AGTCAAACAATTAAATTTACTCTTATCGTTTGAACAAGAACGTTATGAAGATGTGCATTTAATCGACCCAGATTTAACGG
CTTTAGAAATTTCAGCAGCTGAGAAATTGCTACAATACGTTCATACAACGCAAAAACGTGAGCTAAGCCATTTGCAAAAA
TTGGTTCATTATGAAATCAAAGATTACTTGCAAATGTCTTATACGACAAAATCTAGTCTGGATTTATTAGAAAATGCTCG
AACAAGTAAAAAACATGGTAGCCTTTATTGGTTACTAGATGAAACTAAAACGGCTATGGGAATGCGTCTATTGCGCAATT
GGATTGACCGTCCTTTGGTGAACCAAGCACAGATTGAAGAGCGCCAAAATATTGTTCAAGTTTTCCTAGATAATTTCTTT
GAGCGTAGTGATTTGACGGATAGTCTCAAAGGTGTTTATGATATTGAACGTTTAGCGAGTCGTGTGTCATTTGGAAAAGC
TAATCCAAAAGATTTATTACAACTCGGTCATACTTTGGCACAAGTGCCAACGATTAAGGCGATTTTAGAATCGTTTGAGA
GCCCTCACCTTGACAAGCTTGTCAACAACATTGACACTTTGCCAGAGCTAGAATCGCTGATTCGCTCAGCTATTGCCCCA
GATGCCCCTGCTGTTATCACAGAAGGTAGCATTATCCGTACAGGCTTTGATGAGACTTTGGATAAATACCGTAAGGTTAT
GCGCGAGGGGACTAGCTGGATTGCAGAAATTGAAGCTAAGGAACGTGCTGCAAGTGGGATTACCAATCTAAAAATTGATT
ATAATAAAAAAGACGGATACTATTTCCATGTGACAAATTCCAATCTCTCTCTAGTGCCAGATTATTTCTTCCGCAAGGCA
ACGTTGAAAAATTCAGAGCGTTTCGGAACGGCAGAATTGGCAAAAATTGAAGGTGAGATGTTGGAGGCGCGTGAGCAATC
AGCAAGCTTAGAATATGATATTTTCATGCGCGTTCGCGGACAAGTTGAGCGTTACATTACACGTTTGCAAGACTTGGCTA
AGGCGATTTCAACCGTTGACGTTTTACAAAGTTTAGCCGTTGTTGCAGAAAATAATCATTATGTTCGTCCGACGTTCAAC
GATAGCCATGAAATTAAGATTGAAAAAGGTCGTCATGCGGTCGTTGAAAAAGTCATGGGAACGCAAGAATATATTCCTAA
TACGATTACGTTTGATGCCGATATCAACATTCAACTGATTACTGGTCCAAATATGAGTGGTAAATCAACTTATATGCGTC
AACTTGCCTTGACAGTTATTATGGCTCAAATGGGGTCTTACGTAGCTGCTGAAAGTGTCAATTTACCAGTATTTGATGCG
ATTTTCACGCGTATTGGTGCGGCAGATGATTTGATTTCAGGACAGTCAACGTTTATGGTGGAAATGATGGAAGCTAACCA
AGCTATCAAACGTGCAAGTTCTCAATCCTTGATTCTTTTTGATGAGCTAGGTCGTGGTACAGCAACCTATGACGGTATGG
CTTTGGCGCAATCAATCATTGAATATATCCATAATCATATCGGTGCAAAGACCATGTTTGCAACCCATTATCATGAGTTG
ACAGCTTTGTCAACAAGCTTGACGCACCTTATCAATGTTCACGTTGCGACTCTTGAGAAAAATGGTGATGTGACTTTTCT
TCATAAAATTGCAGAAGGTCCAGCAGACAAATCTTACGGAATTCATGTAGCAAAAATTGCTGGTTTACCAGAAGAATTAT
TACAACGTGCGGACAGCATTTTGACGAATTTAGAATCAGGTGCTGCGCAGCTTCAATTGACCCCTGAGGTAGAAGTTGGG
CCAATTACTGTAAAATCTGAAGTAGCAGAACCAGTGGCAGAGCAACTAAGTTTATTTGCTGATGACTCATCTAACCAAGA
AGTGATTGAAGCACTCAAAAAAGTTGATTTGATGAATTTAACACCAATGCAAGCCATGAATGTTATTTATGAATTAAAAA
ATATGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.43	100	0.724
mutS	Pseudomonas stutzeri strain ATCC 17587	37.716	100	0.382