Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   SGGBAA2069_RS11160 Genome accession   NC_015215
Coordinates   2249227..2251170 (-) Length   647 a.a.
NCBI ID   WP_012962624.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2244227..2256170
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGBAA2069_RS11130 (SGGBAA2069_c21910) - 2245027..2246217 (-) 1191 WP_009855167.1 MFS transporter -
  SGGBAA2069_RS12215 - 2246377..2246550 (-) 174 WP_009855168.1 hypothetical protein -
  SGGBAA2069_RS11140 (SGGBAA2069_c21920) - 2246600..2247064 (-) 465 WP_009855169.1 hypothetical protein -
  SGGBAA2069_RS11145 (SGGBAA2069_c21930) - 2247134..2247541 (-) 408 WP_009855170.1 hypothetical protein -
  SGGBAA2069_RS11150 (SGGBAA2069_c21940) - 2247704..2248558 (+) 855 WP_009855171.1 helix-turn-helix domain-containing protein -
  SGGBAA2069_RS11155 (SGGBAA2069_c21950) ruvA 2248632..2249225 (-) 594 WP_009855172.1 Holliday junction branch migration protein RuvA Machinery gene
  SGGBAA2069_RS11160 (SGGBAA2069_c21960) hexB 2249227..2251170 (-) 1944 WP_012962624.1 DNA mismatch repair endonuclease MutL Machinery gene
  SGGBAA2069_RS11165 (SGGBAA2069_c21970) hexA 2251287..2253857 (-) 2571 WP_009855174.1 DNA mismatch repair protein MutS Machinery gene
  SGGBAA2069_RS11170 (SGGBAA2069_c21980) - 2253844..2254200 (-) 357 WP_009855175.1 YlbF family regulator -
  SGGBAA2069_RS11175 (SGGBAA2069_c21990) argR 2254197..2254634 (-) 438 WP_003066930.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73259.42 Da        Isoelectric Point: 5.2201

>NTDB_id=33663 SGGBAA2069_RS11160 WP_012962624.1 2249227..2251170(-) (hexB) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENSIDAGSSQITIEIEEAGLKKIQVTDNGKGIAQDDVALSLHRHATSK
IKNQADLFRIRTLGFRGEAIPSIASISHFTVKTATADENYGTLLVAKGGEIEKQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEVAFSLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMSLISS
AIAESLREQDLIPDALENLAKSSTRGLPKPEQTSLPLKQTDLYYDKERRDFFVKSDTVEEQPVQLFNEVDNSVKEVDKQQ
TSVKYAQRSEVDSQDDEHDNLDFKNKTKINKMIESLDNEESSTFPELDYFGQMHGTYLFAQGNGGLYIIDQHAAQERVKY
EYYREKIGDVDSSLQQLLMPYLFEFSGADFIKLQEKMELLNQVGIYLEPYGNNTFILREHPIWMKEEEIETAVYEMCDML
LLTNEVSVKKYRAELAIMMSCKRSIKANHILDDYSARHLLVQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=33663 SGGBAA2069_RS11160 WP_012962624.1 2249227..2251170(-) (hexB) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
ATGAGTAAAATTATTGAGTTGCCAGAGGTTTTGGCTAACCAAATTGCGGCGGGTGAAGTTATTGAACGACCAGCTAGCGT
TGTCAAAGAATTGGTGGAAAATTCGATTGATGCAGGGAGCAGCCAAATCACCATTGAAATTGAAGAAGCTGGTTTAAAGA
AAATTCAAGTGACAGATAATGGCAAAGGAATTGCTCAAGATGATGTTGCATTAAGTTTGCACCGCCATGCCACAAGTAAA
ATTAAAAATCAAGCTGACCTTTTCCGCATTAGGACGTTAGGTTTTCGTGGCGAAGCGATACCGTCAATTGCCTCCATTAG
TCATTTTACAGTCAAAACAGCAACGGCAGATGAAAATTATGGAACATTGCTAGTAGCCAAAGGTGGCGAAATCGAAAAAC
AAGAACCGATTTCTACACCCGTTGGTACCAAAATTACGGTTGAAAATCTCTTTTATAATACGCCAGCGCGTCTTAAATAC
ATGAAAAGTCTCCAATCCGAATTAGCTCATATTGTTGATGTGGTGAATCGTTTGAGCTTGGCGCACCCAGAGGTGGCTTT
TAGCTTGATTAATGATGGTCGTCAAATGACAACAACATCTGGTACTGGTGATTTGCGACAAGCAATTGCTGGTATTTATG
GGCTTAATACGGCTAAAAAAATGATTGAGATTTCGAATGCTGACCTCGATTTTGAAGTGTCTGGTTACATTAGTCTGCCA
GAATTGACACGAGCGAACCGAAACTATATTACGATTTTGATTAACGGTCGTTATATTAAAAACTTTTTGCTCAATCGTGC
GATTTTGGACGGTTATGGTTCAAAATTGATGGTGGGACGTTTTCCGATTGCTGTTATCGACATTCAAATCGACCCTTATT
TAGCTGATGTCAATGTTCACCCGACGAAGCAAGAAGTTCGTATTTCAAAGGAAAAAGAACTGATGAGCTTAATCAGCTCT
GCTATTGCAGAGAGTTTGCGTGAGCAAGATTTGATACCTGATGCTCTAGAAAATCTGGCGAAATCAAGCACACGTGGGCT
TCCGAAACCAGAGCAAACGAGCCTACCGTTGAAACAAACAGACCTTTATTATGATAAAGAACGTCGTGATTTCTTTGTCA
AGTCAGATACGGTTGAAGAGCAACCAGTACAGTTATTCAATGAGGTTGACAACTCTGTCAAGGAAGTTGACAAGCAACAA
ACATCAGTGAAATATGCGCAGCGTTCCGAAGTAGATAGTCAAGATGATGAACATGATAATCTCGATTTTAAAAACAAGAC
AAAAATCAATAAGATGATTGAAAGTCTTGATAATGAGGAGTCATCAACTTTCCCAGAATTAGATTATTTCGGACAAATGC
ACGGAACGTATCTTTTTGCACAGGGAAATGGTGGGCTTTATATCATTGACCAACACGCTGCTCAAGAACGTGTTAAATAT
GAATATTATCGTGAGAAAATCGGCGACGTTGACAGCTCTTTACAGCAGCTTCTCATGCCATATCTTTTTGAGTTTTCTGG
AGCTGATTTTATTAAGTTGCAAGAAAAAATGGAGCTGTTAAATCAAGTTGGTATTTATCTAGAACCATATGGAAACAACA
CTTTTATTCTCCGTGAACACCCAATTTGGATGAAAGAAGAGGAAATTGAGACGGCTGTTTATGAGATGTGTGATATGCTG
TTGTTGACAAATGAAGTATCGGTGAAGAAATATCGTGCAGAATTGGCAATCATGATGTCATGCAAACGCTCAATCAAAGC
GAATCACATTCTTGATGATTATTCCGCCCGACATCTTTTGGTTCAGTTATCACAATGTAAGAATCCTTATAACTGTCCAC
ATGGACGTCCAGTTCTTGTCAACTTTACCAAAGCTGACATGGAAAAAATGTTCCGCCGTATTCAAGAAAATCACACAAGT
TTAAGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(449-591)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.904

100

0.716

Multiple sequence alignment