Detailed information NTG0336616

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: FZC51_RS02610
• Genome accession: NZ_CP043389
• Coordinates: 542175..543164 (+)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain NRS384-rpoB-H481N-SCV
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 537175..548164

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FZC51_RS02585 (FZC51_02585)	-	537921..538412 (+)	492	WP_000383814.1	DUF948 domain-containing protein	-
FZC51_RS02590 (FZC51_02590)	-	538486..539844 (+)	1359	WP_000193917.1	hypothetical protein	-
FZC51_RS02595 (FZC51_02595)	-	539979..540083 (+)	105	WP_001791758.1	hypothetical protein	-
FZC51_RS02600 (FZC51_02600)	-	540544..541635 (+)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
FZC51_RS02605 (FZC51_02605)	-	541989..542102 (+)	114	WP_001788994.1	hypothetical protein	-
FZC51_RS02610 (FZC51_02610)	ccpA	542175..543164 (+)	990	WP_000219066.1	catabolite control protein A	Regulator
FZC51_RS02615 (FZC51_02615)	-	543262..544431 (-)	1170	WP_001184005.1	acetoin utilization protein AcuC	-
FZC51_RS02620 (FZC51_02620)	-	544456..545088 (-)	633	WP_001015996.1	hypothetical protein	-
FZC51_RS02625 (FZC51_02625)	acsA	545257..546963 (+)	1707	WP_000862083.1	acetate--CoA ligase	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=336616 FZC51_RS02610 WP_000219066.1 542175..543164(+) (ccpA) [Staphylococcus aureus strain NRS384-rpoB-H481N-SCV]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=336616 FZC51_RS02610 WP_000219066.1 542175..543164(+) (ccpA) [Staphylococcus aureus strain NRS384-rpoB-H481N-SCV]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462