Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   EQH46_RS07135 Genome accession   NZ_CP035234
Coordinates   1418037..1419995 (-) Length   652 a.a.
NCBI ID   WP_000748883.1    Uniprot ID   A0A6G2D0S1
Organism   Streptococcus pneumoniae strain TVO_1902277     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1413037..1424995
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH46_RS07115 (EQH46_07465) - 1413758..1414924 (-) 1167 WP_000521387.1 MalY/PatB family protein -
  EQH46_RS07120 (EQH46_07470) - 1414932..1416026 (-) 1095 WP_000031974.1 cystathionine gamma-synthase -
  EQH46_RS07125 - 1416183..1416905 (-) 723 WP_001010367.1 ABC transporter ATP-binding protein -
  EQH46_RS07130 - 1416930..1417865 (-) 936 WP_000768992.1 ABC transporter ATP-binding protein -
  EQH46_RS07135 (EQH46_07480) amiA 1418037..1419995 (-) 1959 WP_000748883.1 peptide ABC transporter substrate-binding protein Regulator
  EQH46_RS07140 (EQH46_07485) - 1420198..1421820 (-) 1623 WP_000017789.1 polysaccharide biosynthesis protein -
  EQH46_RS07145 (EQH46_07490) - 1421926..1423371 (+) 1446 WP_000590316.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  EQH46_RS07150 (EQH46_07495) - 1423414..1423611 (-) 198 WP_000051196.1 CsbD family protein -
  EQH46_RS07155 (EQH46_07500) - 1423712..1424361 (-) 650 Protein_1441 DUF1803 domain-containing protein -
  EQH46_RS07160 (EQH46_07505) - 1424345..1424857 (-) 513 WP_000892254.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72513.97 Da        Isoelectric Point: 5.0565

>NTDB_id=336595 EQH46_RS07135 WP_000748883.1 1418037..1419995(-) (amiA) [Streptococcus pneumoniae strain TVO_1902277]
MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPSSLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSL
AEDWTVSQDGLTYTYKLRKDAKWFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFLMKALVSKSAIEYKKNPNYWDAK
NVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFPNSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTS
DIEKKSTQEAVLNKNFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYGKEWQGINF
ADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGVSSIKQSIESVLGSDNVVIDIQQLTSDEFDS
SGYFAQTAAQKDYDLYHGGWGPDYQDPSTYLDIFSVKNGGVLQNLGLDPGEANDKAKAVGLDTYTQMLEEANKEQDPAKR
YEKYADIQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDEYAKAREKWLKEKEESN
KKAQEELAKHVK

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=336595 EQH46_RS07135 WP_000748883.1 1418037..1419995(-) (amiA) [Streptococcus pneumoniae strain TVO_1902277]
ATGAAAAAGTCTAAGAGCAAATATCTAACCTTGGCAGGTCTTGTCCTGGGTACAGGAGTTTTATTGAGCGCGTGTGGAAA
TTCTAGCACTGCATCAAAAACCTATAACTATGTTTATTCAAGTGATCCATCTAGTTTGAACTATCTAGCAGAAAACCGCG
CAGCAACATCCGATATTGTTGCAAATTTGGTAGACGGGTTATTAGAAAATGACCAATATGGGAATATTATTCCATCATTA
GCAGAGGATTGGACTGTTTCTCAGGACGGTTTGACCTATACCTACAAACTTCGTAAGGATGCCAAGTGGTTTACTTCTGA
GGGAGAAGAATATGCGCCTGTAACTGCCCAGGATTTTGTGACAGGTTTGCAATATGCAGCTGATAAAAAATCAGAAGCTT
TGTATCTAGTGCAGGACTCTGTTGCTGGTTTGGATGACTATATCACTGGTAAAACAAGCGACTTTTCAACTGTCGGTGTC
AAGGCACTTGATGACCAAACGGTTCAATATACTTTGGTTAAACCAGAACTTTACTGGAATTCAAAAACACTTGCAACGAT
ACTTTTTCCTGTTAATGCAGATTTCCTGAAATCAAAAGGGGATGATTTTGGGAAGGCGGATCCATCTAGTATTTTGTACA
ATGGACCTTTCTTGATGAAAGCACTTGTCTCAAAATCTGCTATTGAATATAAGAAAAACCCTAATTACTGGGATGCTAAG
AATGTCTTTGTAGACGATGTGAAATTGACCTACTATGATGGTAGCGACCAAGAATCACTGGAACGTAATTTTACAGCTGG
TGCTTATACTACGGCTCGTCTTTTTCCTAACAGCTCCAGCTATGAAGGGATTAAAGAAAAATACAAAAACAATATCATCT
ATAGTATGCAAAATTCAACTTCATATTTCTTTAATTTTAACCTAGATAGGAAGTCTTACAATTATACTTCTAAAACAAGT
GACATTGAAAAGAAATCGACTCAGGAAGCAGTTCTCAATAAAAACTTCCGTCAGGCTATCAATTTTGCTTTTGACAGAAC
ATCTTATGGGGCTCAGTCCGAAGGGAAAGAAGGTGCAACAAAGATTTTGCGTAACCTAGTGGTTCCTCCAAACTTTGTCA
GTATCAAGGGAAAAGACTTTGGTGAAGTTGTAGCCTCTAAGATGGTCAACTATGGTAAGGAATGGCAAGGTATCAACTTT
GCGGATGGTCAAGACCCTTACTACAATCCTGAGAAAGCCAAGGCTAAGTTTGCGGAAGCTAAGAAAGAACTCGAAGCAAA
GGGTGTTCAATTCCCAATCCACTTGGATAAGACTGTGGAAGTAACAGATAAAGTAGGCATACAAGGAGTTAGTTCTATCA
AACAATCAATTGAATCTGTTTTAGGTTCTGATAATGTAGTGATTGACATTCAGCAATTAACATCAGATGAGTTTGACAGT
TCAGGCTACTTTGCTCAAACAGCTGCTCAGAAAGACTATGATTTATATCATGGCGGTTGGGGACCTGATTATCAAGACCC
GTCAACCTATCTTGATATCTTTAGTGTCAAGAATGGTGGGGTTCTACAAAATCTTGGACTCGACCCTGGTGAAGCCAATG
ACAAGGCTAAGGCAGTTGGACTTGACACTTATACTCAAATGTTGGAAGAGGCTAATAAGGAGCAAGACCCAGCCAAACGT
TATGAGAAATATGCTGATATTCAAGCTTGGTTGATTGATAGTTCTTTAGTTCTTCCAAGTGTTTCGCGTGGGGGAACACC
ATCATTGAGAAGAACCGTACCATTTGCTGCTGCCTATGGTTTAACCGGTACAAAAGGGGTTGAATCATATAAATACCTCA
AAGTACAAGATAAGATTGTCACAACAGACGAATATGCAAAAGCCAGAGAAAAATGGTTGAAAGAAAAAGAAGAATCCAAT
AAAAAAGCCCAAGAAGAATTGGCAAAACATGTCAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(76-517)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G2D0S1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

56.402

100

0.567
  amiA3 Streptococcus thermophilus LMD-9

55.927

100

0.564
  amiA3 Streptococcus thermophilus LMG 18311

55.775

100

0.563

Multiple sequence alignment