Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   FYK42_RS01990 Genome accession   NZ_CP043284
Coordinates   430775..431407 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain WCHEC025985     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 425775..436407
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FYK42_RS01965 (FYK42_01980) yhfG 425907..426074 (+) 168 WP_000736860.1 YhfG family protein -
  FYK42_RS01970 (FYK42_01985) fic 426064..426666 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  FYK42_RS01975 (FYK42_01990) pabA 426698..427261 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  FYK42_RS01980 (FYK42_01995) argD 427347..428567 (+) 1221 WP_000963785.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  FYK42_RS01985 (FYK42_02000) yhfK 428634..430724 (-) 2091 WP_001356225.1 YccS/YhfK family putative transporter -
  FYK42_RS01990 (FYK42_02005) crp 430775..431407 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  FYK42_RS01995 (FYK42_02010) yhfA 431709..432113 (+) 405 WP_001148908.1 OsmC family protein -
  FYK42_RS02000 (FYK42_02015) prkB 432168..433037 (-) 870 WP_001274680.1 phosphoribulokinase -
  FYK42_RS02005 (FYK42_02020) yheU 433091..433309 (-) 219 WP_000907085.1 YheU family protein -
  FYK42_RS02010 (FYK42_02025) yheT 433303..434325 (-) 1023 WP_000057380.1 hydrolase -
  FYK42_RS02015 (FYK42_02030) yheS 434325..436238 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=336096 FYK42_RS01990 WP_000242755.1 430775..431407(-) (crp) [Escherichia coli strain WCHEC025985]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=336096 FYK42_RS01990 WP_000242755.1 430775..431407(-) (crp) [Escherichia coli strain WCHEC025985]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment