Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FX998_RS14250 Genome accession   NZ_CP043227
Coordinates   2919859..2920449 (-) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain Ec-050     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2914859..2925449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FX998_RS14235 (FX998_14235) uhpT 2915499..2916890 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  FX998_RS14240 (FX998_14240) uhpC 2917028..2918347 (-) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  FX998_RS14245 (FX998_14245) uhpB 2918357..2919859 (-) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  FX998_RS14250 (FX998_14250) letA 2919859..2920449 (-) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  FX998_RS14255 (FX998_14255) ilvN 2920524..2920814 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  FX998_RS14260 (FX998_14260) ilvB 2920818..2922506 (-) 1689 WP_000168475.1 acetolactate synthase large subunit -
  FX998_RS14265 (FX998_14265) ivbL 2922612..2922710 (-) 99 WP_001300753.1 ilvB operon leader peptide IvbL -
  FX998_RS14270 (FX998_14270) - 2923102..2924321 (+) 1220 Protein_2787 ISL3-like element ISKox3 family transposase -
  FX998_RS14275 (FX998_14275) tisB 2924598..2924687 (+) 90 WP_001054909.1 type I toxin-antitoxin system toxin TisB -
  FX998_RS25705 ysdE 2924811..2924885 (-) 75 WP_211180519.1 protein YsdE -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=335889 FX998_RS14250 WP_000633668.1 2919859..2920449(-) (letA) [Escherichia coli strain Ec-050]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=335889 FX998_RS14250 WP_000633668.1 2919859..2920449(-) (letA) [Escherichia coli strain Ec-050]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAGCTGCTAAGCCAGCTGCCGAAAGGTATGGCGACGATTATGCTCTCCGTT
CACGACAGTCCTGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTTTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGTGAACGCCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCACCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment