Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FYA02_RS11635 Genome accession   NZ_CP043217
Coordinates   2297352..2298011 (+) Length   219 a.a.
NCBI ID   WP_032205041.1    Uniprot ID   -
Organism   Escherichia coli O80:H26 strain EC-107     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2292352..2303011
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FYA02_RS11610 (FYA02_11610) ygiS 2293635..2295242 (-) 1608 WP_001295629.1 ABC transporter substrate-binding protein -
  FYA02_RS11615 (FYA02_11615) mqsA 2295375..2295770 (-) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  FYA02_RS11620 (FYA02_11620) mqsR 2295772..2296068 (-) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  FYA02_RS11625 (FYA02_11625) ygiV 2296273..2296755 (-) 483 WP_000183505.1 GyrI-like domain-containing protein -
  FYA02_RS11630 (FYA02_11630) ygiW 2296808..2297200 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  FYA02_RS11635 (FYA02_11635) ciaR 2297352..2298011 (+) 660 WP_032205041.1 quorum sensing response regulator transcription factor QseB Regulator
  FYA02_RS11640 (FYA02_11640) qseC 2298008..2299357 (+) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  FYA02_RS11645 (FYA02_11645) ygiZ 2299403..2299735 (-) 333 WP_000917684.1 DUF2645 family protein -
  FYA02_RS11650 (FYA02_11650) mdaB 2300054..2300635 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  FYA02_RS11655 (FYA02_11655) ygiN 2300666..2300980 (+) 315 WP_000958598.1 putative quinol monooxygenase -
  FYA02_RS11660 (FYA02_11660) parE 2301028..2302920 (-) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24717.65 Da        Isoelectric Point: 6.9850

>NTDB_id=335790 FYA02_RS11635 WP_032205041.1 2297352..2298011(+) (ciaR) [Escherichia coli O80:H26 strain EC-107]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLSSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=335790 FYA02_RS11635 WP_032205041.1 2297352..2298011(+) (ciaR) [Escherichia coli O80:H26 strain EC-107]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCAGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

37.445

100

0.388
  ciaR Streptococcus pneumoniae D39

37.445

100

0.388
  ciaR Streptococcus pneumoniae R6

37.445

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

37.445

100

0.388
  ciaR Streptococcus mutans UA159

35.874

100

0.365

Multiple sequence alignment