Detailed information NTG0033574

Bioinformatically predicted

Overview

• Name: comGE
• Type: Machinery gene
• Locus tag: SGGBAA2069_RS00775
• Genome accession: NC_015215
• Coordinates: 124408..124701 (+)
• Length: 97 a.a.
• NCBI ID: WP_012961329.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 119408..129701

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SGGBAA2069_RS00750 (SGGBAA2069_c01050)	-	121401..121769 (+)	369	WP_009853228.1	DUF1033 family protein	-
SGGBAA2069_RS00755 (SGGBAA2069_c01060)	comGA	121838..122779 (+)	942	WP_012961327.1	competence type IV pilus ATPase ComGA	Machinery gene
SGGBAA2069_RS00760	comGB	122661..123746 (+)	1086	WP_012961328.1	competence type IV pilus assembly protein ComGB	Machinery gene
SGGBAA2069_RS00765 (SGGBAA2069_c01070)	comGC	123746..124039 (+)	294	WP_009853231.1	competence type IV pilus major pilin ComGC	Machinery gene
SGGBAA2069_RS00770 (SGGBAA2069_c01080)	comGD	124023..124454 (+)	432	WP_009853232.1	competence type IV pilus minor pilin ComGD	Machinery gene
SGGBAA2069_RS00775 (SGGBAA2069_c01090)	comGE	124408..124701 (+)	294	WP_012961329.1	competence type IV pilus minor pilin ComGE	Machinery gene
SGGBAA2069_RS00780 (SGGBAA2069_c01100)	comGF	124655..125122 (+)	468	WP_012961330.1	competence type IV pilus minor pilin ComGF	Machinery gene
SGGBAA2069_RS00785 (SGGBAA2069_c01110)	comGG	125094..125408 (+)	315	WP_009853235.1	competence type IV pilus minor pilin ComGG	Machinery gene
SGGBAA2069_RS00790 (SGGBAA2069_c01120)	comGH	125481..126437 (+)	957	WP_009853236.1	class I SAM-dependent methyltransferase	Machinery gene
SGGBAA2069_RS00795 (SGGBAA2069_c01130)	-	126490..127689 (+)	1200	WP_009853237.1	acetate kinase	-
SGGBAA2069_RS00800 (SGGBAA2069_c01140)	-	127851..128051 (+)	201	WP_012961332.1	helix-turn-helix transcriptional regulator	-
SGGBAA2069_RS00805 (SGGBAA2069_c01150)	-	128061..128270 (+)	210	WP_009853239.1	hypothetical protein	-
SGGBAA2069_RS00810 (SGGBAA2069_c01160)	-	128283..128735 (+)	453	WP_009853240.1	hypothetical protein	-
SGGBAA2069_RS00815 (SGGBAA2069_c01170)	-	128747..129385 (+)	639	WP_009853241.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 97 a.a.
• Molecular weight: 10952.89 Da
• Isoelectric Point: 8.4757

>NTDB_id=33574 SGGBAA2069_RS00775 WP_012961329.1 124408..124701(+) (comGE) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
MVNIKRQKLKAYILLESLIALGLLAMITSIVLGEIDKNRQSMQESLRQQEALNVATMAVQTGQNHLKMNGVEVEIIKKDG
EVYVYEGKTEILHVKKD

Nucleotide

• Length: 294 bp

>NTDB_id=33574 SGGBAA2069_RS00775 WP_012961329.1 124408..124701(+) (comGE) [Streptococcus gallolyticus subsp. gallolyticus ATCC BAA-2069]
GTGGTAAATATAAAAAGACAGAAACTAAAAGCTTACATACTCCTTGAAAGCTTGATAGCACTAGGATTGTTAGCGATGAT
TACGAGTATTGTTTTAGGGGAAATTGATAAAAATAGGCAGTCTATGCAAGAAAGTTTACGGCAGCAGGAAGCTCTTAATG
TGGCAACAATGGCTGTGCAAACAGGACAAAATCATTTGAAGATGAATGGTGTTGAGGTTGAGATTATCAAAAAAGATGGA
GAGGTCTATGTTTATGAGGGGAAAACGGAAATATTACACGTTAAAAAAGACTAG

Domains

Predicted by InterProScan.

• Type II secretory pathway pseudopilin (ComGE) (13-94)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE	Streptococcus mutans UA140	47.917	98.969	0.474
comGE	Streptococcus mutans UA159	47.917	98.969	0.474
comGE/cglE	Streptococcus mitis SK321	42.553	96.907	0.412
comGE/cglE	Streptococcus pneumoniae Rx1	41.489	96.907	0.402
comGE/cglE	Streptococcus pneumoniae D39	41.489	96.907	0.402
comGE/cglE	Streptococcus pneumoniae R6	41.489	96.907	0.402
comGE/cglE	Streptococcus pneumoniae TIGR4	41.489	96.907	0.402
comGE/cglE	Streptococcus mitis NCTC 12261	41.489	96.907	0.402