Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   EM803_RS00760 Genome accession   NZ_CP035105
Coordinates   152122..152865 (+) Length   247 a.a.
NCBI ID   WP_000660524.1    Uniprot ID   A0AAI8F143
Organism   Helicobacter pylori strain Hpbs2     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 147122..157865
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EM803_RS00735 panD 149272..149622 (+) 351 WP_000142212.1 aspartate 1-decarboxylase -
  EM803_RS00740 - 149633..149926 (+) 294 WP_128480957.1 YbaB/EbfC family nucleoid-associated protein -
  EM803_RS00745 - 149926..150921 (+) 996 WP_128481772.1 PDZ domain-containing protein -
  EM803_RS00750 comB6 150929..151984 (+) 1056 WP_128481771.1 P-type conjugative transfer protein TrbL Machinery gene
  EM803_RS00755 comB7 152000..152125 (+) 126 WP_075668089.1 comB7 lipoprotein Machinery gene
  EM803_RS00760 comB8 152122..152865 (+) 744 WP_000660524.1 virB8 family protein Machinery gene
  EM803_RS00765 comB9 152865..153836 (+) 972 WP_128480958.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  EM803_RS00770 comB10 153829..154965 (+) 1137 WP_128480959.1 DNA type IV secretion system protein ComB10 Machinery gene
  EM803_RS00775 - 155035..156447 (+) 1413 WP_128480960.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  EM803_RS00780 gmd 156462..157607 (+) 1146 WP_031214491.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28684.91 Da        Isoelectric Point: 8.9546

>NTDB_id=334473 EM803_RS00760 WP_000660524.1 152122..152865(+) (comB8) [Helicobacter pylori strain Hpbs2]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKVTRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=334473 EM803_RS00760 WP_000660524.1 152122..152865(+) (comB8) [Helicobacter pylori strain Hpbs2]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTATTTAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATTGTTTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGCAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGGGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGTTTGCAAAGCAGCTCTAAAGTGTGGCAACGCTTTGAAGATTTGATCAAAACGCAAAACAGCATTTAT
GCACAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAGTCACTCGCTACAGCATCACTGAAATC
GCGCCAACTAATAGAGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972

Multiple sequence alignment