Detailed information NTG0334335

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: EPZ47_RS20610
• Genome accession: NZ_CP035088
• Coordinates: 4723714..4725960 (-)
• Length: 748 a.a.
• NCBI ID: WP_135846485.1
• Uniprot ID: A0A4P7PL18
• Organism: Pseudomonas viciae strain 11K1
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 4718714..4730960

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EPZ47_RS20575 (EPZ47_20570)	murB	4719097..4720116 (-)	1020	WP_135846479.1	UDP-N-acetylmuramate dehydrogenase	-
EPZ47_RS20580 (EPZ47_20575)	-	4720113..4720577 (-)	465	WP_135846480.1	low molecular weight protein-tyrosine-phosphatase	-
EPZ47_RS20585 (EPZ47_20580)	kdsB	4720577..4721341 (-)	765	WP_135846481.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
EPZ47_RS20590 (EPZ47_20585)	-	4721338..4721523 (-)	186	WP_003179363.1	Trm112 family protein	-
EPZ47_RS20595 (EPZ47_20590)	lpxK	4721547..4722557 (-)	1011	WP_135846482.1	tetraacyldisaccharide 4'-kinase	-
EPZ47_RS20600 (EPZ47_20595)	-	4722557..4722985 (-)	429	WP_135846483.1	ExbD/TolR family protein	-
EPZ47_RS20605 (EPZ47_20600)	exbB	4722982..4723617 (-)	636	WP_178084272.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
EPZ47_RS20610 (EPZ47_20605)	comA	4723714..4725960 (-)	2247	WP_135846485.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EPZ47_RS20615 (EPZ47_20610)	-	4726106..4726621 (+)	516	WP_135846486.1	DUF2062 domain-containing protein	-
EPZ47_RS20620 (EPZ47_20615)	-	4726786..4727565 (-)	780	WP_135846487.1	ABC transporter permease	-
EPZ47_RS20625 (EPZ47_20620)	-	4727562..4728494 (-)	933	WP_135846488.1	ABC transporter ATP-binding protein	-
EPZ47_RS20630 (EPZ47_20625)	-	4728628..4729251 (-)	624	WP_135846489.1	glutathione S-transferase family protein	-
EPZ47_RS20635 (EPZ47_20630)	-	4729296..4729955 (-)	660	WP_135846490.1	transglutaminase-like domain-containing protein	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 81235.31 Da
• Isoelectric Point: 10.2037

>NTDB_id=334335 EPZ47_RS20610 WP_135846485.1 4723714..4725960(-) (comA) [Pseudomonas viciae strain 11K1]
MRTGLVAFALGLLAPVFLPALPPFWLIATMPVLGLMVLPFRTYPLGFFLFGLAWACLSAQLALADRLPAVLDGETRWVEG
RVVGLPQHSEDVVRFELADARSRRTRLPASMRLAWFGGPPVSSGERWRLAVKLKRPAGLLNPHGFDYEAWLLSRGIGATG
TVKDGLRLQAAQGAWRDGVRQALAQVDAHGRSGALAALVLGDGSGLSREDWQVLQDTGTVHLLVISGQHIGLLAGLVYLL
VAGAARYGLWPVGLPWLPWACALAFAAALGYGLLAGFEVPVRRACAMIGLVLLWRLRFKHPDPWWAWLLAFVGVLVFDPL
ASLRPGFWLSFAAVAILMFTFGARLGPWRWWQTWTRAQWLVALGLCPLLVILGLPVSLSGPLVNLLAVPWISLLVLPPAL
LGTALLPVPLLGEGLLWIAGGLLDWLFKGLALVAGRMPAWVPVSIPLWAWCIAALGAFLLLLPKGVPLRVLGWPMLLLMV
FPPRESVPQGHAEIWHLDVGQGLAVLVRTRRHSLLYDAGPRFGEADAGERVVLPTLRKLGVQALDLMLLSHADADHAGGA
RAVRSGLPTRRVISGDPAALPDELQAGACDSGEGWEWDGVRFQLWQWSAARESNQKSCVLLVEAGGERLLLTGDIDSHAE
QALLDGPLAAPSQWLAAPHHGSRSSSSMALLARLNPHSVLISRGQGNAFGHPHPRVIARYRRLGLAIYDSAEQGAIRLQL
GAFEPPFTQARQRRYWRDPPPVGPQAKH

Nucleotide

• Length: 2247 bp

>NTDB_id=334335 EPZ47_RS20610 WP_135846485.1 4723714..4725960(-) (comA) [Pseudomonas viciae strain 11K1]
ATGCGCACAGGGTTGGTCGCGTTTGCACTGGGGCTGTTGGCCCCGGTTTTTTTACCGGCATTGCCGCCGTTTTGGCTGAT
TGCAACCATGCCGGTGCTGGGGTTGATGGTGTTGCCGTTTCGCACCTACCCGCTGGGTTTTTTTCTGTTCGGGTTGGCCT
GGGCCTGCCTGTCGGCGCAGTTGGCATTGGCCGACCGGTTGCCTGCCGTGCTGGATGGCGAAACCCGCTGGGTCGAAGGG
CGTGTCGTCGGCTTGCCGCAGCACAGCGAGGACGTGGTGCGTTTCGAACTGGCCGATGCCCGTTCGCGTCGCACCCGGCT
ACCGGCGTCGATGCGTCTGGCCTGGTTCGGTGGTCCGCCCGTCAGCAGCGGCGAGCGATGGCGATTGGCTGTGAAGCTCA
AACGGCCGGCCGGATTACTGAACCCACACGGTTTCGACTATGAAGCCTGGCTGTTGAGCCGAGGCATCGGGGCGACCGGC
ACGGTGAAGGATGGCCTTCGTCTGCAAGCGGCCCAAGGTGCGTGGCGCGACGGCGTGCGACAGGCTCTGGCCCAAGTGGA
TGCCCACGGGCGCTCCGGTGCGCTGGCGGCCTTGGTGCTTGGCGACGGCAGCGGGCTGAGCCGCGAAGATTGGCAGGTAC
TGCAAGACACTGGCACCGTCCATTTACTGGTGATTTCCGGGCAGCACATCGGTCTGCTCGCCGGTCTGGTGTACCTGCTG
GTGGCCGGTGCGGCGCGTTATGGGCTGTGGCCGGTGGGTCTGCCGTGGTTGCCTTGGGCTTGTGCGCTGGCCTTCGCCGC
AGCCCTGGGCTACGGCTTGCTCGCTGGGTTCGAGGTGCCGGTGCGGCGGGCTTGCGCGATGATCGGCCTGGTGCTCCTCT
GGCGCTTGCGCTTCAAACACCCGGACCCCTGGTGGGCATGGCTGCTGGCCTTTGTCGGGGTGCTGGTGTTCGATCCGCTG
GCCAGCCTGCGGCCGGGGTTCTGGCTGTCGTTTGCGGCGGTGGCGATATTGATGTTCACCTTTGGCGCTCGCCTGGGGCC
CTGGCGCTGGTGGCAAACCTGGACCCGTGCCCAATGGCTGGTTGCGCTCGGCCTGTGTCCGTTACTGGTGATATTGGGCT
TGCCGGTCAGCCTCAGCGGGCCGCTGGTAAATCTGCTGGCGGTGCCCTGGATCAGCCTGTTGGTGTTGCCGCCGGCGTTG
CTCGGCACGGCGTTGTTGCCGGTGCCGTTGCTCGGTGAAGGGCTGCTGTGGATAGCCGGTGGCTTGCTCGATTGGCTGTT
CAAGGGGCTGGCGCTGGTTGCCGGGCGGATGCCGGCATGGGTTCCTGTTTCGATTCCGCTCTGGGCCTGGTGTATTGCCG
CCCTCGGGGCTTTTTTGCTGCTGCTGCCCAAGGGGGTGCCGCTGCGGGTGCTGGGGTGGCCAATGCTGCTGCTGATGGTT
TTTCCACCGCGAGAAAGCGTGCCGCAAGGCCATGCCGAAATCTGGCACCTGGACGTCGGCCAAGGGCTTGCGGTGCTCGT
GCGCACCCGTCGCCATAGCCTGCTTTACGATGCCGGGCCGCGCTTCGGCGAGGCCGACGCGGGCGAGCGCGTCGTGCTGC
CGACTTTGCGCAAACTGGGGGTACAGGCGTTGGATCTGATGCTGCTCAGCCATGCCGACGCCGATCACGCCGGCGGCGCT
CGCGCGGTGCGCAGCGGGCTGCCAACGAGGCGGGTGATCAGCGGCGATCCTGCCGCGCTGCCTGATGAGCTGCAAGCCGG
AGCATGCGACAGCGGCGAAGGTTGGGAGTGGGACGGGGTCAGGTTCCAATTGTGGCAATGGTCCGCTGCCCGTGAAAGCA
ACCAGAAGTCCTGCGTCTTGCTGGTCGAGGCCGGCGGCGAGCGCTTGCTGCTGACTGGCGACATCGATAGTCATGCTGAA
CAGGCCTTGCTCGACGGGCCCCTGGCGGCCCCGAGCCAGTGGCTGGCCGCCCCGCATCATGGCAGTCGCAGCTCATCGTC
AATGGCGCTGCTGGCGCGTCTGAATCCTCATTCGGTGCTGATCTCCCGGGGGCAAGGCAACGCGTTCGGTCATCCGCATC
CCCGGGTGATCGCTCGTTACCGTCGGTTGGGCCTGGCGATCTACGACAGTGCCGAACAGGGCGCCATTCGTCTGCAACTG
GGGGCCTTTGAACCCCCCTTCACCCAGGCCAGGCAGCGGCGGTATTGGCGTGATCCGCCGCCTGTCGGGCCGCAGGCCAA
ACATTGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (22-165)

• Metallo-beta-lactamase superfamily (Lactamase_B) (498-672)

• Competence protein (Competence) (198-464)

3D structure

• AlphaFold DB: A0A4P7PL18

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	61.944	96.257	0.596
comA	Ralstonia pseudosolanacearum GMI1000	32.665	100	0.37