Detailed information
Bioinformatically predicted
Overview
| Name | comM | Type | Regulator |
| Locus tag | SPT_RS09455 | Genome accession | NC_012469 |
| Coordinates | 1782944..1783564 (-) | Length | 206 a.a. |
| NCBI ID | WP_000839909.1 | Uniprot ID | A0A098Z2X2 |
| Organism | Streptococcus pneumoniae Taiwan19F-14 | ||
| Function | fratricide immunity (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1771399..1812468 | 1782944..1783564 | within | 0 |
Gene organization within MGE regions
Location: 1771399..1812468
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SPT_RS09385 (SPT_1889) | - | 1771696..1772247 (-) | 552 | WP_001111247.1 | hypothetical protein | - |
| SPT_RS09390 (SPT_1890) | - | 1772237..1772434 (-) | 198 | WP_000890144.1 | hypothetical protein | - |
| SPT_RS09395 (SPT_1891) | - | 1772438..1773232 (-) | 795 | WP_001101215.1 | hypothetical protein | - |
| SPT_RS09400 (SPT_1892) | - | 1773640..1774065 (-) | 426 | WP_000204068.1 | hypothetical protein | - |
| SPT_RS09405 (SPT_1893) | - | 1774194..1774553 (-) | 360 | WP_000749821.1 | ImmA/IrrE family metallo-endopeptidase | - |
| SPT_RS09410 | - | 1774599..1774805 (-) | 207 | WP_000366087.1 | hypothetical protein | - |
| SPT_RS09415 (SPT_1894) | - | 1774792..1774953 (-) | 162 | WP_000289348.1 | helix-turn-helix domain-containing protein | - |
| SPT_RS09420 (SPT_1895) | lytA | 1775312..1776268 (-) | 957 | WP_000405240.1 | N-acetylmuramoyl-L-alanine amidase LytA | - |
| SPT_RS09425 (SPT_1897) | - | 1776644..1778014 (-) | 1371 | WP_001036271.1 | MATE family efflux transporter | - |
| SPT_RS09430 (SPT_1898) | recA | 1778321..1779487 (-) | 1167 | WP_001085462.1 | recombinase RecA | Machinery gene |
| SPT_RS09435 (SPT_1899) | cinA | 1779542..1780798 (-) | 1257 | WP_000642704.1 | competence/damage-inducible protein A | Machinery gene |
| SPT_RS09440 (SPT_1900) | brpA | 1780883..1781899 (-) | 1017 | WP_000239278.1 | biofilm formation/cell division transcriptional regulator BrpA | - |
| SPT_RS09445 (SPT_1901) | - | 1781907..1782425 (-) | 519 | WP_000455536.1 | GNAT family N-acetyltransferase | - |
| SPT_RS09450 (SPT_1902) | tsaE | 1782415..1782858 (-) | 444 | WP_000288230.1 | tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE | - |
| SPT_RS09455 (SPT_1903) | comM | 1782944..1783564 (-) | 621 | WP_000839909.1 | hypothetical protein | Regulator |
| SPT_RS09460 (SPT_1904) | - | 1783870..1784733 (-) | 864 | WP_001093609.1 | helix-turn-helix domain-containing protein | - |
| SPT_RS13265 (SPT_1905) | - | 1784924..1785094 (+) | 171 | WP_001227863.1 | PhrA family quorum-sensing system peptide | - |
| SPT_RS09470 (SPT_1907) | - | 1785496..1785810 (+) | 315 | WP_000420682.1 | YdcP family protein | - |
| SPT_RS09475 (SPT_1908) | - | 1785826..1786212 (+) | 387 | WP_000985015.1 | YdcP family protein | - |
| SPT_RS09480 (SPT_1909) | - | 1786241..1787626 (+) | 1386 | WP_000813488.1 | FtsK/SpoIIIE domain-containing protein | - |
| SPT_RS12265 | - | 1787629..1787781 (+) | 153 | WP_000879507.1 | hypothetical protein | - |
| SPT_RS09485 (SPT_1910) | mobT | 1787804..1789009 (+) | 1206 | WP_000398284.1 | MobT family relaxase | - |
| SPT_RS09490 (SPT_1911) | - | 1789052..1789273 (+) | 222 | WP_001009056.1 | hypothetical protein | - |
| SPT_RS09495 (SPT_1912) | - | 1789390..1789887 (+) | 498 | WP_000342539.1 | antirestriction protein ArdA | - |
| SPT_RS09500 (SPT_1913) | - | 1789976..1790368 (+) | 393 | WP_000723888.1 | conjugal transfer protein | - |
| SPT_RS09505 (SPT_1914) | - | 1790352..1792799 (+) | 2448 | WP_000331160.1 | ATP-binding protein | - |
| SPT_RS09510 (SPT_1915) | - | 1792802..1794979 (+) | 2178 | WP_012677156.1 | CD3337/EF1877 family mobilome membrane protein | - |
| SPT_RS09515 (SPT_1916) | - | 1794976..1795977 (+) | 1002 | WP_000769868.1 | lysozyme family protein | - |
| SPT_RS09520 (SPT_1917) | - | 1795974..1796906 (+) | 933 | WP_001224318.1 | conjugal transfer protein | - |
| SPT_RS13480 | - | 1797220..1797267 (+) | 48 | Protein_1810 | hypothetical protein | - |
| SPT_RS09525 (SPT_1919) | tet(M) | 1797283..1799202 (+) | 1920 | WP_000691729.1 | tetracycline resistance ribosomal protection protein Tet(M) | - |
| SPT_RS09535 | - | 1799566..1799811 (+) | 246 | WP_001813542.1 | hypothetical protein | - |
| SPT_RS09540 (SPT_1922) | - | 1799808..1800143 (+) | 336 | WP_000806926.1 | hypothetical protein | - |
| SPT_RS09545 (SPT_1923) | - | 1800156..1800524 (+) | 369 | WP_000567222.1 | hypothetical protein | - |
| SPT_RS09550 (SPT_1924) | - | 1800511..1800810 (+) | 300 | WP_001072467.1 | DUF5960 family protein | - |
| SPT_RS09555 (SPT_1925) | msr(D) | 1800928..1802391 (-) | 1464 | WP_000420313.1 | ABC-F type ribosomal protection protein Msr(D) | - |
| SPT_RS09560 (SPT_1926) | mef(A) | 1802511..1803728 (-) | 1218 | WP_000417519.1 | macrolide efflux MFS transporter Mef(A) | - |
| SPT_RS09565 (SPT_1927) | - | 1804114..1804284 (-) | 171 | WP_000873143.1 | hypothetical protein | - |
| SPT_RS12275 | - | 1804806..1804997 (+) | 192 | WP_001860868.1 | cysteine-rich KTR domain-containing protein | - |
| SPT_RS09575 (SPT_1928) | - | 1805057..1805410 (-) | 354 | WP_001227347.1 | helix-turn-helix transcriptional regulator | - |
| SPT_RS09580 (SPT_1929) | - | 1805915..1806337 (+) | 423 | WP_000804885.1 | sigma-70 family RNA polymerase sigma factor | - |
| SPT_RS09585 | - | 1806334..1806564 (+) | 231 | WP_000857133.1 | helix-turn-helix domain-containing protein | - |
| SPT_RS13130 | - | 1806790..1807041 (-) | 252 | WP_001845478.1 | hypothetical protein | - |
| SPT_RS09590 (SPT_1930) | - | 1807025..1807228 (+) | 204 | WP_000814511.1 | excisionase | - |
| SPT_RS09595 (SPT_1931) | - | 1807310..1808527 (+) | 1218 | WP_001291561.1 | tyrosine-type recombinase/integrase | - |
| SPT_RS09600 (SPT_1933) | - | 1809418..1811433 (+) | 2016 | WP_000732395.1 | DUF1430 domain-containing protein | - |
| SPT_RS09605 (SPT_1934) | - | 1811435..1812067 (+) | 633 | WP_000571425.1 | ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 206 a.a. Molecular weight: 23540.66 Da Isoelectric Point: 10.1254
>NTDB_id=33408 SPT_RS09455 WP_000839909.1 1782944..1783564(-) (comM) [Streptococcus pneumoniae Taiwan19F-14]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF
Nucleotide
Download Length: 621 bp
>NTDB_id=33408 SPT_RS09455 WP_000839909.1 1782944..1783564(-) (comM) [Streptococcus pneumoniae Taiwan19F-14]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comM | Streptococcus pneumoniae D39 |
99.515 |
100 |
0.995 |
| comM | Streptococcus pneumoniae R6 |
99.515 |
100 |
0.995 |
| comM | Streptococcus pneumoniae TIGR4 |
99.515 |
100 |
0.995 |
| comM | Streptococcus mitis NCTC 12261 |
38.462 |
94.66 |
0.364 |
| comM | Streptococcus mitis SK321 |
38.462 |
94.66 |
0.364 |